Plendil and Cilostazol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plendil (felodipine) and Cilostazol (cilostazol). Common drug interactions include dermatitis among females and oedema peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Plendil and Cilostazol. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

What is Cilostazol?

Cilostazol has active ingredients of cilostazol. It is often used in arteriosclerosis of the extremities. eHealthMe is studying from 7,877 Cilostazol users. Check the latest studies of Cilostazol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

16 people who take Plendil and Cilostazol together, and have interactions are studied.

Plendil and Cilostazol drug interactions.

What are the common drug interactions of Plendil and Cilostazol, by gender? *:

female:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Hypoaesthesia (reduced sense of touch or sensation)
Myalgia (muscle pain)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Pain
Peau d'orange (orange peel skin)
Pruritus (severe itching of the skin)
Rash
Rash macular (small, flat red spots)

male:

Oedema peripheral (superficial swelling)
Pain
Back pain
Bladder cancer
Bladder mass
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Cardiorenal syndrome (kidney failure and heart failure)

What are the common drug interactions of Plendil and Cilostazol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Intervertebral disc protrusion (spinal disc protrusion)
Intervertebral disc space narrowing (spinal disc space narrowing)
Joint effusion (presence of extra fluid in joint covering)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Ligament disorder (disease of ligament)
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Lymphadenitis (inflammation or enlargement of a lymph node)
Mastoiditis (infection of mastoid bone)
Memory impairment
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Joint range of motion decreased (disease of joint movement)
Lichenification (thickening and hardening of the skin)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Oedema (fluid collection in tissue)
Pigmentation disorder (disturbances of human skin colour)
Pulmonary function test decreased
Skin fibrosis (fibrous tissue formation on skin)
Skin tightness

What are the existing conditions these people have? *

Bone Disorder: 11 people, 68.75%
Multiple Myeloma (cancer of the plasma cells): 10 people, 62.50%
High Blood Cholesterol: 4 people, 25.00%
Cardiac Failure Congestive: 3 people, 18.75%
Stress And Anxiety: 1 person, 6.25%
Peripheral Vascular Disorder: 1 person, 6.25%
Nuclear Magnetic Resonance Imaging Abdominal: 1 person, 6.25%
Neuropathy Peripheral (surface nerve damage): 1 person, 6.25%
Hypersensitivity: 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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