Plendil and Meridia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plendil (felodipine) and Meridia (sibutramine hydrochloride). Common drug interactions include hunger among females.

The phase IV clinical study analyzes what interactions people have when they take Plendil and Meridia. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

What is Meridia?

Meridia has active ingredients of sibutramine hydrochloride. It is often used in weight loss. eHealthMe is studying from 6,939 Meridia users. Check the latest studies of Meridia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

14 people who take Plendil and Meridia together, and have interactions are studied.

What are the common drug interactions of Plendil and Meridia, by gender? *:

female:

Hunger
Abdominal distension
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Euphoric mood (excessively happy but may become angry or irritable)
Fall
Irritable bowel syndrome
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Nonspecific reaction (unspecified reaction)
Pneumonia

male:

n/a

What are the common drug interactions of Plendil and Meridia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Tooth disorder (tooth disease)

30-39:

n/a

40-49:

Hunger
Abdominal distension
Appetite disorder (abnormal eating habits)
Nausea (feeling of having an urge to vomit)
Taste disturbance
Weight increased

50-59:

Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dry mouth
Euphoric mood (excessively happy but may become angry or irritable)
Nonspecific reaction (unspecified reaction)
Pruritus (severe itching of the skin)

60+:

Abdominal pain upper
Aphasia (damage to the parts of the brain that control language)
Tinnitus (a ringing in the ears)
Urinary tract infection
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depression
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Fall
Irritable bowel syndrome
Nephrolithiasis (calculi in the kidneys)

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Plendil and Meridia?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously