Plendil and Procardia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plendil (felodipine) and Procardia (nifedipine). Common drug interactions include skin exfoliation among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Plendil and Procardia. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

What is Procardia?

Procardia has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 15,151 Procardia users. Check the latest studies of Procardia.

On Aug, 02, 2026

38 people who take Plendil and Procardia together, and have interactions are studied.

Plendil and Procardia drug interactions.

What are the common drug interactions of Plendil and Procardia, by gender? *:

female:

Skin exfoliation (removal of the oldest dead skin cells)
Skin fissures (a crack in the skin)
Skin induration (an abnormally hard spot or area on the skin)
Abdominal distension
Activities of daily living impaired
Dysstasia (difficulty in standing)
Insomnia (sleeplessness)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Mobility decreased (ability to move is reduced)
Skin haemorrhage (bleeding into skin)

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Dizziness
Gastritis (inflammation of stomach)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Paralysed
Peripheral vascular disorder
Road traffic accident
Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Plendil and Procardia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac failure congestive
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

30-39:

Tooth disorder (tooth disease)

40-49:

Asthenia (weakness)
Abdominal distension
Cardiomegaly (increased size of heart than normal)
Dyspepsia (indigestion)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Pulmonary hypertension (increase in blood pressure in the lung artery)
Weight increased
Affect lability (emotional incontinence)

50-59:

Erythema (redness of the skin)
Injury
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Pain
Pain in extremity
Peripheral coldness
Pruritus (severe itching of the skin)

60+:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Dysstasia (difficulty in standing)
Gastritis (inflammation of stomach)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Injury
Insomnia (sleeplessness)
Pain
Peripheral vascular disorder

What are the existing conditions these people have? *

Venous Pressure Increased: 4 people, 10.53%
Stable Angina (a constant chest pain): 3 people, 7.89%
Joint Pain: 2 people, 5.26%
Ill-Defined Disorder: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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