Polysporin and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Polysporin (bacitracin zinc; polymyxin b sulfate) and Colace (docusate ). Common drug interactions include excoriation among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Polysporin and Colace. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Polysporin?

Polysporin has active ingredients of bacitracin zinc; polymyxin b sulfate. eHealthMe is studying from 517 Polysporin users. Check the latest studies of Polysporin.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Jul, 10, 2026

19 people who take Polysporin and Colace together, and have interactions are studied.

Polysporin and Colace drug interactions.

What are the common drug interactions of Polysporin and Colace, by gender? *:

female:

Excoriation (to tear or wear off the skin of)
Faecal incontinence (a lack of control over passing stool)
Fatigue (feeling of tiredness)
Feeling cold
Flatulence (flatus expelled through the anus)
Fungal skin infection
Gait disturbance
Gout (uric acid crystals building up in the body)
Haemorrhage (bleeding)
Hallucination (an experience involving the perception of something not present)

male:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Weight decreased
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Alanine aminotransferase increased
Arthralgia (joint pain)
Aspartate aminotransferase increased
Asthenia (weakness)
Blood calcium increased
Blood parathyroid hormone increased

What are the common drug interactions of Polysporin and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Intestinal perforation (complete penetration of the wall of the intestine)
Neoplasm malignant (cancer tumour)

60+:

Hyperhidrosis (abnormally increased sweating)
Dehydration (dryness resulting from the removal of water)
Vomiting
Weight decreased
Renal tubular necrosis (death of kidney tubules)
Acute lymphocytic leukaemia (cancer of the white blood cells)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Alanine aminotransferase increased
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 10.53%
Pain: 2 people, 10.53%
High Blood Pressure: 2 people, 10.53%
Endocarditis (inflammation in heart muscle): 2 people, 10.53%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 10.53%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 10.53%
Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 2 people, 10.53%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.53%
Depression: 2 people, 10.53%
Mitral Valve Disease (disease of mitral valve of heart): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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