Pomalyst and Vagifem drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pomalyst (pomalidomide) and Vagifem (estradiol). Common drug interactions include death among females.
The phase IV clinical study analyzes what interactions people have when they take Pomalyst and Vagifem. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Pomalyst?
Pomalyst has active ingredients of pomalidomide. eHealthMe is studying from 80,400 Pomalyst users. Check the latest studies of Pomalyst.
What is Vagifem?
Vagifem has active ingredients of estradiol. It is often used in vulvovaginal dryness. eHealthMe is studying from 6,263 Vagifem users. Check the latest studies of Vagifem.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
23 people who take Pomalyst and Vagifem together, and have interactions are studied.

What are the common drug interactions of Pomalyst and Vagifem, by gender? *:
female:
- Death
- Muscle spasms (muscle contraction)
- Nasopharyngitis (inflammation of the nasopharynx)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Pneumonia
- Pyrexia (fever)
- Skin discolouration (change of skin colour)
- White blood cell count decreased
- Adverse event
- Aphthous ulcer (mouth ulcer)
male:
n/a
What are the common drug interactions of Pomalyst and Vagifem, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Nasopharyngitis (inflammation of the nasopharynx)
- Influenza
- Pneumonia
60+:
- Death
- Muscle spasms (muscle contraction)
- Drug hypersensitivity
- Drug intolerance (drug sensitivity)
- Heart rate decreased
- Hypersensitivity
- Rash
- Tongue coated
- Tremor (trembling or shaking movements in one or more parts of your body)
- Pyrexia (fever)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 21 people, 91.30%
* Approximation only. Some reports may have incomplete information.
Do you take Pomalyst and Vagifem?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Pomalyst and Vagifem:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pomalyst:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vagifem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pomalyst and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vagifem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pomalidomide and estradiol (the active ingredients of Pomalyst and Vagifem, respectively), and Pomalyst and Vagifem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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