Potassium bicarbonate and Lactulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Potassium bicarbonate (potassium) and Lactulose (lactulose). Common drug interactions include general physical health deterioration among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Potassium bicarbonate and Lactulose. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Potassium bicarbonate?

Potassium bicarbonate has active ingredients of potassium. eHealthMe is studying from 453 Potassium bicarbonate users. Check the latest studies of Potassium bicarbonate.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

39 people who take Potassium bicarbonate and Lactulose together, and have interactions are studied.

Potassium bicarbonate and Lactulose drug interactions.

What are the common drug interactions of Potassium Bicarbonate and Lactulose, by gender? *:

female:

General physical health deterioration (weak health status)
Blood lactate dehydrogenase increased
Parainfluenzae virus infection
Blood creatinine increased
Cardiac failure
Circulatory collapse
Conjunctivitis (pink eye)
Gamma-glutamyltransferase increased
Lymphocytosis (an increase in the number or proportion of lymphocytes in the blood)
Pruritus (severe itching of the skin)

male:

Drug hypersensitivity
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Hepatic failure (liver failure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Alanine aminotransferase increased
Aspartate aminotransferase increased
Asthenia (weakness)
Burkholderia test positive
Confusional state

What are the common drug interactions of Potassium Bicarbonate and Lactulose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Kidney infection
Blindness
Tunnel vision (the loss of peripheral vision with retention of central vision)

50-59:

Drug hypersensitivity
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Anaemia (lack of blood)
Anal abscess
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypokalaemia (low potassium)
Neutropenia (an abnormally low number of neutrophils)

60+:

General physical health deterioration (weak health status)
Blood lactate dehydrogenase increased
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Febrile neutropenia (fever with reduced white blood cells)
Leukopenia (less number of white blood cells in blood)
Osteoporosis (bones weak and more likely to break)

What are the existing conditions these people have? *

Hypokalemia (low potassium): 5 people, 12.82%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 10.26%
Infection: 4 people, 10.26%
Burkitt Lymphoma (cancer of the lymphatic system): 4 people, 10.26%
Type 2 Diabetes: 4 people, 10.26%
Pain: 4 people, 10.26%
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 4 people, 10.26%
Cardiac Failure: 3 people, 7.69%
Dyspnea (difficult or laboured breathing): 3 people, 7.69%
High Blood Pressure: 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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