Potassium chloride and Actonel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Potassium chloride (potassium chloride) and Actonel (risedronate sodium). Common drug interactions include depressed mood among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Potassium chloride and Actonel. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.
What is Potassium chloride?
Potassium chloride has active ingredients of potassium chloride. It is often used in hypokalemia. eHealthMe is studying from 29,249 Potassium chloride users. Check the latest studies of Potassium chloride.
What is Actonel?
Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
78 people who take Potassium chloride and Actonel together, and have interactions are studied.

What are the common drug interactions of Potassium Chloride and Actonel, by gender? *:
female:
- Depressed mood
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Pain in extremity
- Pneumonia fungal
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
- Femur fracture
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
male:
- Fall
- Pain in extremity
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- Tibia fracture (fracture of lower leg bone)
- Anxiety
- Aggression
- Bipolar disorder (mood disorder)
- Depression
- Hallucination (an experience involving the perception of something not present)
- Insomnia (sleeplessness)
What are the common drug interactions of Potassium Chloride and Actonel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Activities of daily living impaired
- Arthralgia (joint pain)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Comminuted fracture (bone has broken into several pieces)
- Cystitis interstitial (unknown cause characterized by bladder pain)
- Fall
- Femur fracture
- Haemoglobin decreased
- Mobility decreased (ability to move is reduced)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
30-39:
- Interstitial lung disease
40-49:
- Anaemia (lack of blood)
- Aids dementia complex (most common and clinically important cns complications of late hiv-1 infection)
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Cytomegalovirus colitis (an inflammation of the colon from virus)
- Delirium (wild excitement)
- Depressed mood
- Diarrhoea
- Herpes zoster
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
50-59:
- Infusion related reaction
- Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
- Oesophagitis (inflammation of oesophagus)
- Pyrexia (fever)
- Skeletal injury (bone and supporting muscle injury)
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- Thoracic vertebral fracture
- Anaemia (lack of blood)
- Asthenia (weakness)
- Electrolyte imbalance
60+:
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Cardiac failure
- Fall
- Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
- Oedema peripheral (superficial swelling)
- Pneumonia
- Skeletal injury (bone and supporting muscle injury)
- Alanine aminotransferase increased
- Bile duct stone
What are the existing conditions these people have? *
- High Blood Pressure: 11 people, 14.10%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 10.26%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 10.26%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 10.26%
- Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 7.69%
- Diabetes: 6 people, 7.69%
- Hiv Infection: 6 people, 7.69%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 6.41%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 6.41%
- Dyslipidaemia (abnormal amount of lipids): 5 people, 6.41%
* Approximation only. Some reports may have incomplete information.
Do you take Potassium chloride and Actonel?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Potassium chloride (29,249 reports)
- Actonel (29,369 reports)
Browse all drug interactions of Potassium chloride and Actonel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Potassium chloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Actonel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Potassium chloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actonel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on potassium chloride and risedronate sodium (the active ingredients of Potassium chloride and Actonel, respectively), and Potassium chloride and Actonel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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