Potassium iodide and Aldactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Potassium iodide (potassium iodide) and Aldactone (spironolactone). Common drug interactions include hypoalbuminaemia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Potassium iodide and Aldactone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Potassium iodide?

Potassium iodide has active ingredients of potassium iodide. It is often used in thyroid diseases. eHealthMe is studying from 1,919 Potassium iodide users. Check the latest studies of Potassium iodide.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 46,063 Aldactone users. Check the latest studies of Aldactone.

On Jul, 08, 2026

17 people who take Potassium iodide and Aldactone together, and have interactions are studied.

Potassium iodide and Aldactone drug interactions.

What are the common drug interactions of Potassium Iodide and Aldactone, by gender? *:

female:

Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypoproteinaemia (too little prolactin circulating in the blood)
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)
Oropharyngeal pain
Periodontitis (inflammation of the tissue around the teeth)
Pneumonia
Pyrexia (fever)
Rhinorrhoea (watery mucus discharge from the nose)

male:

Abdominal pain
Accident
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Emotional disorder
Epididymitis (pain in the scrotum or testicle)
Erectile dysfunction
Fatigue (feeling of tiredness)
Gynaecomastia (enlargement of the gland tissue of the male breast)
Haematochezia (passage of stools containing blood)

What are the common drug interactions of Potassium Iodide and Aldactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Device related infection
Hyperthyroidism (over activity of the thyroid gland)

20-29:

Diarrhoea
Hyperammonaemia
Hyperthyroidism (over activity of the thyroid gland)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Right ventricular failure (right half of the heart fails to work)
Cardiac failure
Chest discomfort
Weight decreased

30-39:

Renal disorder (kidney disease)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Restlessness (not able to rest)
Right ventricular failure (right half of the heart fails to work)
Somnolence (a state of near-sleep, a strong desire for sleep)
Urine output decreased
Vomiting
Cardiac failure
Pulmonary hypertension (increase in blood pressure in the lung artery)
Abdominal pain

40-49:

Clostridial infection (infectious conditions by clostridium bacteria)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Epistaxis (bleed from the nose)
Haemorrhage (bleeding)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypoproteinaemia (too little prolactin circulating in the blood)
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)

50-59:

Abdominal pain
Accident
Anaemia (lack of blood)
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac murmur (an heart sound in valve abnormality)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cold sweat

60+:

Chronic kidney disease
Dehydration (dryness resulting from the removal of water)
Septic shock (shock due to blood infection)
Somnolence (a state of near-sleep, a strong desire for sleep)
Staphylococcal infection (an infection with staphylococcus bacteria)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypokalaemia (low potassium)
Infected skin ulcer
Leukocytosis (increased white blood cells)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 41.18%
Right Ventricular Failure (right half of the heart fails to work): 6 people, 35.29%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 35.29%
Hyperthyroidism (over activity of the thyroid gland): 5 people, 29.41%
Cardiac Failure Congestive: 2 people, 11.76%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
Cardiac Failure: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Potassium iodide and Aldactone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously