Pradaxa and Azopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pradaxa (dabigatran etexilate mesylate) and Azopt (brinzolamide). Common drug interactions include urinary incontinence among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Pradaxa and Azopt. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.

What is Azopt?

Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.

On Jul, 14, 2026

71 people who take Pradaxa and Azopt together, and have interactions are studied.

What are the common drug interactions of Pradaxa and Azopt, by gender? *:

female:

Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urinary tract infection
Ankle fracture
Apathy
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Blood potassium decreased
Cardiac flutter (abnormal heart rhythm)
Erythema (redness of the skin)
Flushing (the warm, red condition of human skin)
Fungal skin infection

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Arthralgia (joint pain)
Dark circles under eyes
Decreased appetite
Disease progression
Femur fracture
Glossodynia (a burning or painful sensation in the tongue)
Haematemesis (vomiting of blood)
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)

What are the common drug interactions of Pradaxa and Azopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaemia (lack of blood)
Dizziness
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haemorrhage (bleeding)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Tremor (trembling or shaking movements in one or more parts of your body)

20-29:

n/a

30-39:

n/a

40-49:

Oxygen saturation decreased
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Asthenia (weakness)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Fall
Gait disturbance
Muscular weakness (muscle weakness)
Oesophageal pain

50-59:

Haematoma (collection of blood outside the blood vessels)
Pneumonia

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anaemia (lack of blood)
Cellulitis (infection under the skin)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Haemorrhage subcutaneous (bleeding from skin)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Abdominal discomfort
Blood urine present
Vomiting

What are the existing conditions these people have? *

High Blood Cholesterol: 15 people, 21.13%
High Blood Pressure: 12 people, 16.90%
Cardiac Disorder: 8 people, 11.27%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 8.45%
Thyroid Diseases: 5 people, 7.04%
Oesophageal Candidiasis (fungal infection of oesophagus): 5 people, 7.04%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 7.04%
Cardiac Failure: 5 people, 7.04%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 5.63%
Diabetes: 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

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