Pradaxa and Solu-cortef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pradaxa (dabigatran etexilate mesylate) and Solu-cortef (hydrocortisone sodium succinate). Common drug interactions include cough among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Pradaxa and Solu-cortef. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.



On Jul, 28, 2026

12 people who take Pradaxa and Solu-cortef together, and have interactions are studied.

Pradaxa and Solu-cortef drug interactions.

What are the common drug interactions of Pradaxa and Solu-Cortef, by gender? *:

female:

  1. Cough
  2. Rash
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Burning sensation
  5. Cold sweat
  6. Discomfort
  7. Ear infection
  8. Fatigue (feeling of tiredness)
  9. Feeding disorder (when children refuse to eat certain food groups)
  10. Fungal infection

male:

  1. Cellulitis (infection under the skin)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Burning sensation
  4. Chest discomfort
  5. Dyspnoea (difficult or laboured respiration)
  6. Eye swelling
  7. Flushing (the warm, red condition of human skin)
  8. Infusion related reaction
  9. Pruritus (severe itching of the skin)
  10. Throat tightness

What are the common drug interactions of Pradaxa and Solu-Cortef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Oesophageal candidiasis (fungal infection of oesophagus)

30-39:

n/a

40-49:

n/a

50-59:

  1. Cellulitis (infection under the skin)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

  1. Cushingoid (obesity and weakening of the muscles)
  2. Oedema (fluid collection in tissue)
  3. Burning sensation
  4. Cardiac arrest
  5. Chest discomfort
  6. Cough
  7. Dyspnoea (difficult or laboured respiration)
  8. Eye swelling
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Flushing (the warm, red condition of human skin)

What are the existing conditions these people have? *

  1. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 33.33%
  2. Weakness: 3 people, 25.00%
  3. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 25.00%
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 25.00%
  5. Cellulitis (infection under the skin): 3 people, 25.00%
  6. Constipation: 3 people, 25.00%
  7. Depression: 3 people, 25.00%
  8. Diarrhea: 3 people, 25.00%
  9. Enlarged Prostate: 3 people, 25.00%
  10. Groin Infection (infection in groin): 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pradaxa and Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pradaxa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pradaxa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Solu-cortef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dabigatran etexilate mesylate and hydrocortisone sodium succinate (the active ingredients of Pradaxa and Solu-cortef, respectively), and Pradaxa and Solu-cortef (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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