Pralatrexate and Ondansetron drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pralatrexate (pralatrexate) and Ondansetron (ondansetron). Common drug interactions include blood sodium decreased among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Pralatrexate and Ondansetron. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Pralatrexate?
Pralatrexate has active ingredients of pralatrexate. eHealthMe is studying from 231 Pralatrexate users. Check the latest studies of Pralatrexate.
What is Ondansetron?
Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.
11 people who take Pralatrexate and Ondansetron together, and have interactions are studied.

What are the common drug interactions of Pralatrexate and Ondansetron, by gender? *:
female:
- Blood sodium decreased
- Haematocrit decreased
- Haemoglobin decreased
- Oral candidiasis (fungal infection of mouth)
- Thrombocytopenia (decrease of platelets in blood)
- Blood albumin decreased
- Blood chloride decreased
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
male:
- Dyspnoea (difficult or laboured respiration)
- Blood creatinine increased
- White blood cell count decreased
- Abdominal pain
- Anaemia (lack of blood)
- Asthenia (weakness)
- B-cell lymphoma (blood cancer affecting b cells)
- Blood albumin decreased
- Blood chloride decreased
- Blood urea increased
What are the common drug interactions of Pralatrexate and Ondansetron, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Dyspnoea (difficult or laboured respiration)
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- B-cell lymphoma (blood cancer affecting b cells)
- Blood creatinine increased
- Confusional state
- Cough
- Failure to thrive (inadequate weight gain and physical growth in children)
- Haematocrit decreased
60+:
- Blood albumin decreased
- Blood chloride decreased
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
- Abdominal pain
- Anaemia (lack of blood)
- Asthenia (weakness)
- Blood creatinine increased
- Blood urea increased
- Contusion (a type of hematoma of tissue in which capillaries)
What are the existing conditions these people have? *
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 36.36%
- T-Cell Lymphoma (a blood cell cancer): 1 person, 9.09%
- Pulmonary Oedema (fluid accumulation in the lungs): 1 person, 9.09%
- Pneumonia: 1 person, 9.09%
- Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 1 person, 9.09%
- Pain: 1 person, 9.09%
- Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 1 person, 9.09%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 9.09%
- Hodgkin's Lymphoma (cancer originating from white blood cells): 1 person, 9.09%
- Hodgkin's Disease Recurrent (cancer originating from white blood cells -recurrent): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Pralatrexate and Ondansetron?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pralatrexate (231 reports)
- Ondansetron (122,738 reports)
Browse all drug interactions of Pralatrexate and Ondansetron:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pralatrexate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ondansetron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pralatrexate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ondansetron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pralatrexate and ondansetron (the active ingredients of Pralatrexate and Ondansetron, respectively), and Pralatrexate and Ondansetron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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