Praluent and Cozaar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Praluent (alirocumab) and Cozaar (losartan potassium). Common drug interactions include nausea among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Praluent and Cozaar. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Praluent?

Praluent has active ingredients of alirocumab. It is often used in high blood cholesterol. eHealthMe is studying from 24,963 Praluent users. Check the latest studies of Praluent.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.



On Jul, 12, 2026

47 people who take Praluent and Cozaar together, and have interactions are studied.

Praluent and Cozaar drug interactions.

What are the common drug interactions of Praluent and Cozaar, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Tibia fracture (fracture of lower leg bone)
  3. Blood glucose increased
  4. Injection site bruising
  5. Arthralgia (joint pain)
  6. Influenza
  7. Myalgia (muscle pain)
  8. Nasal discomfort
  9. Injection site swelling
  10. Abdominal pain upper

male:

  1. Arthralgia (joint pain)
  2. Death
  3. Tongue discolouration (colour change of tongue)
  4. Asthma
  5. Bladder disorder
  6. Blood bilirubin increased
  7. Blood pressure systolic increased
  8. Cardiac failure
  9. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  10. Decreased appetite

What are the common drug interactions of Praluent and Cozaar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Myalgia (muscle pain)
  2. Nasal discomfort
  3. Arthralgia (joint pain)
  4. Groin pain
  5. Joint swelling
  6. Pain in extremity
  7. Peripheral swelling
  8. Vaginal haemorrhage (vaginal bleeding)

50-59:

  1. Tibia fracture (fracture of lower leg bone)
  2. Alanine aminotransferase increased
  3. Aspartate aminotransferase increased
  4. Hepatic enzyme increased

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Blood glucose increased
  3. Abdominal pain upper
  4. Anxiety
  5. Aphonia (inability to produce voice)
  6. Constipation
  7. Cough
  8. Death
  9. Dizziness
  10. Glossodynia (a burning or painful sensation in the tongue)

What are the existing conditions these people have? *

  1. Hyperlipidaemia (presence of excess lipids in the blood): 11 people, 23.40%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 23.40%
  3. Depression: 8 people, 17.02%
  4. Stable Angina (a constant chest pain): 6 people, 12.77%
  5. Enlarged Prostate: 5 people, 10.64%
  6. Vitamin D Decreased: 4 people, 8.51%
  7. Rickets (softening of bones): 4 people, 8.51%
  8. Quit Smoking: 4 people, 8.51%
  9. Erection Problems: 4 people, 8.51%
  10. Eosinophilia (eosinophil count in the peripheral blood exceeds): 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

Do you take Praluent and Cozaar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Praluent and Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Praluent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Praluent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cozaar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on alirocumab and losartan potassium (the active ingredients of Praluent and Cozaar, respectively), and Praluent and Cozaar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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