Pramine and Armodafinil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramine (imipramine hydrochloride) and Armodafinil (armodafinil). Common drug interactions include fatigue among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pramine and Armodafinil. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Armodafinil?

Armodafinil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 4,136 Armodafinil users. Check the latest studies of Armodafinil.

On Jul, 13, 2026

19 people who take Pramine and Armodafinil together, and have interactions are studied.

Pramine and Armodafinil drug interactions.

What are the common drug interactions of Pramine and Armodafinil, by gender? *:

female:

Fatigue (feeling of tiredness)
Vomiting
Weight decreased
Asthenia (weakness)
Fall
Gait disturbance
Hallucination (an experience involving the perception of something not present)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Idiopathic intracranial hypertension (elevated cerebrospinal fluid pressure of unknown cause)
Irritable bowel syndrome

male:

Chronic kidney disease
Renal impairment (severely reduced kidney function)
Gait disturbance
Gastric disorder (disease of stomach)
Initial insomnia (feeling of inadequate or poor-quality sleep)
Insomnia (sleeplessness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nasal disorder (diseases of nose)
Periorbital disorder (gum inflammation to serious disease that results in major damage to the soft tissue and bone that support the teeth)
Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Pramine and Armodafinil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aggression
Dizziness
Enuresis (repeated inability to control urination)
Incoherent (talking in a confused and unclear way)
Nasopharyngitis (inflammation of the nasopharynx)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Psychotic disorder
Vomiting

20-29:

n/a

30-39:

Idiopathic intracranial hypertension (elevated cerebrospinal fluid pressure of unknown cause)

40-49:

Chronic kidney disease
Renal impairment (severely reduced kidney function)
Fatigue (feeling of tiredness)
Irritable bowel syndrome
Renal failure (kidney dysfunction)
Abdominal discomfort
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Apnoea (suspension of external breathing)
Asthenia (weakness)

50-59:

Abnormal sleep-related event
Aortic dilatation
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Periorbital disorder (gum inflammation to serious disease that results in major damage to the soft tissue and bone that support the teeth)
Somnambulism (sleep walking)
Weight decreased
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Decreased appetite
Enuresis (repeated inability to control urination)
Feeling drunk

60+:

n/a

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 47.37%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 3 people, 15.79%
Pain: 3 people, 15.79%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 15.79%
Cardiac Disorder: 3 people, 15.79%
Inflammation: 3 people, 15.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
Bladder Disorder: 1 person, 5.26%
Blood Pressure Abnormal: 1 person, 5.26%
Diabetes: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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