Pramine and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramine (imipramine hydrochloride) and Colace (docusate ). Common drug interactions include anxiety among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Pramine and Colace. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Jul, 28, 2026

69 people who take Pramine and Colace together, and have interactions are studied.

What are the common drug interactions of Pramine and Colace, by gender? *:

female:

Anxiety
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Hallucination (an experience involving the perception of something not present)
Injury
Nightmare (unpleasant dream)
Post-traumatic stress disorder
Urinary tract infection
Abdominal pain
Blood urine present
Bruxism (habitual grinding of the teeth, typically during sleep)

male:

Pyrexia (fever)
Dizziness
Abdominal discomfort
Abnormal dreams
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Arthralgia (joint pain)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Collapse (sudden functional breakdown)

What are the common drug interactions of Pramine and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Agitation (state of anxiety or nervous excitement)
Burning sensation
Depression
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Implant site infection
Implant site scar
Incontinence (lack of moderation or self-control)
Insomnia (sleeplessness)

30-39:

Dizziness
Dehydration (dryness resulting from the removal of water)
Pallor
Pyrexia (fever)
Blood pressure decreased
Blood pressure increased
Dysuria (painful or difficult urination)
Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment
Panic attack

40-49:

Migraine (headache)
Muscle rupture (tear in muscle)
Nightmare (unpleasant dream)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Post-traumatic stress disorder
Renal failure (kidney dysfunction)
Sensory disturbance (sense disturbance)
Spinal cord abscess (pus in spinal cord)
Urinary hesitation (difficulty in beginning the flow of urine)
Chronic kidney disease

50-59:

Oral surgery
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Cardiac failure congestive
Anaemia (lack of blood)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
Leukopenia (less number of white blood cells in blood)
Nausea (feeling of having an urge to vomit)
Pneumonia
Pyrexia (fever)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 21.74%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 20.29%
Pain: 13 people, 18.84%
High Blood Pressure: 9 people, 13.04%
Muscle Spasms (muscle contraction): 8 people, 11.59%
Multiple Myeloma (cancer of the plasma cells): 6 people, 8.70%
Migraine (headache): 5 people, 7.25%
High Blood Cholesterol: 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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