Pramine and Hytrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramine (imipramine hydrochloride) and Hytrin (terazosin hydrochloride). Common drug interactions include alanine aminotransferase increased among females and red blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Pramine and Hytrin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Hytrin?

Hytrin has active ingredients of terazosin hydrochloride. It is often used in prostate examination abnormal. eHealthMe is studying from 7,501 Hytrin users. Check the latest studies of Hytrin.



On Aug, 03, 2026

19 people who take Pramine and Hytrin together, and have interactions are studied.

Pramine and Hytrin drug interactions.

What are the common drug interactions of Pramine and Hytrin, by gender? *:

female:

  1. Alanine aminotransferase increased
  2. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  3. Aspartate aminotransferase increased
  4. Back pain
  5. Blood alkaline phosphatase nos increased
  6. Blood bilirubin increased
  7. Clamminess (moist, sticky, and cold to the touch)
  8. Faeces discoloured
  9. Gamma-glutamyltransferase increased
  10. Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)

male:

  1. Red blood cell count decreased
  2. Dry skin
  3. Skin discolouration (change of skin colour)
  4. Skin induration (an abnormally hard spot or area on the skin)
  5. Abdominal distension
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Nightmare (unpleasant dream)
  8. White blood cell count decreased
  9. Oedema lower limb (fluid collection in tissue of lower leg)
  10. Platelet count decreased

What are the common drug interactions of Pramine and Hytrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hyperammonaemia
  2. Lethargy (tiredness)
  3. Weight decreased

50-59:

  1. Abdominal pain
  2. Alanine aminotransferase increased
  3. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  4. Aspartate aminotransferase increased
  5. Back pain
  6. Blood alkaline phosphatase nos increased
  7. Blood bilirubin increased
  8. Clamminess (moist, sticky, and cold to the touch)
  9. Colitis pseudomembranous (antibiotic-associated diarrhoea)
  10. Faeces discoloured

60+:

  1. Red blood cell count decreased
  2. Dry skin
  3. Skin discolouration (change of skin colour)
  4. Skin induration (an abnormally hard spot or area on the skin)
  5. Abdominal distension
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Nightmare (unpleasant dream)
  8. White blood cell count decreased
  9. Oedema lower limb (fluid collection in tissue of lower leg)
  10. Platelet count decreased

What are the existing conditions these people have? *

  1. Sleep Apnea Syndrome: 4 people, 21.05%
  2. Nuclear Magnetic Resonance Imaging Brain: 4 people, 21.05%
  3. Headache (pain in head): 4 people, 21.05%
  4. Brain Stem Syndrome: 4 people, 21.05%

* Approximation only. Some reports may have incomplete information.

Do you take Pramine and Hytrin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pramine and Hytrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hytrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hytrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on imipramine hydrochloride and terazosin hydrochloride (the active ingredients of Pramine and Hytrin, respectively), and Pramine and Hytrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: