Pramine and Lovenox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramine (imipramine hydrochloride) and Lovenox (enoxaparin sodium). Common drug interactions include cellulitis among females and activated partial thromboplastin time prolonged among males.

The phase IV clinical study analyzes what interactions people have when they take Pramine and Lovenox. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Lovenox?

Lovenox has active ingredients of enoxaparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 48,149 Lovenox users. Check the latest studies of Lovenox.



On Jul, 13, 2026

20 people who take Pramine and Lovenox together, and have interactions are studied.

Pramine and Lovenox drug interactions.

What are the common drug interactions of Pramine and Lovenox, by gender? *:

female:

  1. Cellulitis (infection under the skin)
  2. Chest discomfort
  3. Chronic kidney disease
  4. Congestive cardiomyopathy (weakening of heart muscle)
  5. Crying
  6. Dehydration (dryness resulting from the removal of water)
  7. Depressed mood
  8. Disturbance in attention
  9. Dizziness
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Activated partial thromboplastin time prolonged
  2. Alanine aminotransferase increased
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  5. Calcium deficiency (lack of calcium)
  6. Catheter site haemorrhage (bleeding at catheter site)
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  9. Confusional state
  10. Constipation

What are the common drug interactions of Pramine and Lovenox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Insomnia (sleeplessness)
  2. Intervertebral disc degeneration (spinal disc degeneration)
  3. Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Pain
  7. Pyrexia (fever)
  8. Renal failure chronic (long lasting kidney dysfunction)
  9. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  10. Rhinitis allergic (inflammation of the nasal airways due to allergy)

60+:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Uterine disorder
  6. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  7. Incontinence (lack of moderation or self-control)
  8. Intervertebral disc degeneration (spinal disc degeneration)
  9. Chronic kidney disease
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 8 people, 40.00%
  2. Pain: 5 people, 25.00%
  3. Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 15.00%
  4. Localised Infection (infection at the single location): 2 people, 10.00%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
  6. Nosocomial Infection (infection from hospital): 2 people, 10.00%
  7. Multiple Myeloma (cancer of the plasma cells): 2 people, 10.00%
  8. Migraine (headache): 2 people, 10.00%
  9. Gastric Ph Decreased: 1 person, 5.00%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pramine and Lovenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lovenox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lovenox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on imipramine hydrochloride and enoxaparin sodium (the active ingredients of Pramine and Lovenox, respectively), and Pramine and Lovenox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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