Pramine and Q10 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramine (imipramine hydrochloride) and Q10 (coenzyme q - 10). Common drug interactions include ocular discomfort among females and urticaria among males.

The phase IV clinical study analyzes what interactions people have when they take Pramine and Q10. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Q10?

Q10 has active ingredients of coenzyme q - 10. eHealthMe is studying from 34,259 Q10 users. Check the latest studies of Q10.



On Jul, 13, 2026

40 people who take Pramine and Q10 together, and have interactions are studied.

Pramine and Q10 drug interactions.

What are the common drug interactions of Pramine and Q10, by gender? *:

female:

  1. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  2. Ocular hyperaemia (an abnormally large amount of blood in eye)
  3. Osteonecrosis (death of bone)
  4. Pain
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
  7. Pericardial effusion (fluid around the heart)
  8. Photophobia (extreme sensitivity to light)
  9. Physical disability
  10. Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone)

male:

  1. Urticaria (rash of round, red welts on the skin that itch intensely)
  2. Anxiety
  3. Body height decreased
  4. Diarrhoea
  5. Dislocation of vertebra
  6. Dry mouth
  7. Dysphonia (speech disorder attributable to a disorder of phonation)
  8. Exostosis (formation of new bone on the surface of a bone)
  9. Fall
  10. Flatulence (flatus expelled through the anus)

What are the common drug interactions of Pramine and Q10, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  2. Restless legs syndrome (a powerful urge to move your legs)

30-39:

  1. Neuralgia (pain in one or more nerves)

40-49:

  1. Dehydration (dryness resulting from the removal of water)

50-59:

  1. Drug ineffective
  2. Drug administration error
  3. Injection site bruising
  4. Restless legs syndrome (a powerful urge to move your legs)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Stress
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anxiety
  9. Back pain
  10. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

60+:

  1. Fatigue (feeling of tiredness)
  2. Anxiety
  3. Blood pressure increased
  4. Body height decreased
  5. Confusional state
  6. Dehydration (dryness resulting from the removal of water)
  7. Drug ineffective
  8. Dry mouth
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Excoriation (to tear or wear off the skin of)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 30.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 25.00%
  3. Stress And Anxiety: 5 people, 12.50%
  4. High Blood Cholesterol: 4 people, 10.00%
  5. Cardiac Disorder: 4 people, 10.00%
  6. Muscle Spasms (muscle contraction): 3 people, 7.50%
  7. High Blood Pressure: 3 people, 7.50%
  8. Sleep Disorder: 2 people, 5.00%
  9. Seasonal Allergy (allergic condition due to certain season): 2 people, 5.00%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pramine and Q10:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Q10:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Q10 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on imipramine hydrochloride and coenzyme q - 10 (the active ingredients of Pramine and Q10, respectively), and Pramine and Q10 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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