Pramine and Vasotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramine (imipramine hydrochloride) and Vasotec (enalapril maleate). Common drug interactions include cardiac failure congestive among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Pramine and Vasotec. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

On Jul, 15, 2026

17 people who take Pramine and Vasotec together, and have interactions are studied.

What are the common drug interactions of Pramine and Vasotec, by gender? *:

female:

Cardiac failure congestive
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Haematoma (collection of blood outside the blood vessels)
Haemoglobin decreased
Hepatic function abnormal
Muscle haemorrhage (bleeding in muscle)
Neuropathy peripheral (surface nerve damage)
Oedema lower limb (fluid collection in tissue of lower leg)
Pain in limb
Pruritus (severe itching of the skin)

male:

Nausea (feeling of having an urge to vomit)
Acute myocardial infarction (acute heart attack)
Application site pigmentation changes
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Bacterial infection
Blood chloride decreased
Blood sodium decreased
Blood urine
Chills (felling of cold)

What are the common drug interactions of Pramine and Vasotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Neuropathy peripheral (surface nerve damage)
Type 2 diabetes mellitus

60+:

Nausea (feeling of having an urge to vomit)
Acute myocardial infarction (acute heart attack)
Nephrolithiasis (calculi in the kidneys)
Scar
Weight decreased
Application site pigmentation changes
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Bacterial infection
Blood chloride decreased

What are the existing conditions these people have? *

Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 2 people, 11.76%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 11.76%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.76%
Cardiac Failure Congestive: 2 people, 11.76%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.88%
Depression: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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