Prandin and Symlin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prandin (repaglinide) and Symlin (pramlintide acetate). Common drug interactions include drug ineffective among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Prandin and Symlin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Prandin?

Prandin has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 4,680 Prandin users. Check the latest studies of Prandin.

What is Symlin?

Symlin has active ingredients of pramlintide acetate. It is often used in diabetes. eHealthMe is studying from 3,359 Symlin users. Check the latest studies of Symlin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

13 people who take Prandin and Symlin together, and have interactions are studied.

What are the common drug interactions of Prandin and Symlin, by gender? *:

female:

Drug ineffective
Listless (lack of interest, energy, or spirit)
Pallor
Vomiting
Weight increased
Blood glucose decreased
Hyperhidrosis (abnormally increased sweating)
Abdominal pain upper
Activities of daily living impaired
Chest discomfort

male:

Blood glucose increased
Drug effect decreased
Injury
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

What are the common drug interactions of Prandin and Symlin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Blood glucose decreased
Hyperhidrosis (abnormally increased sweating)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Blood glucose increased
Dizziness
Drug ineffective
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Injection site pain
Injection site rash
Muscle spasms (muscle contraction)
Oedema peripheral (superficial swelling)
Weight increased

60+:

Nausea (feeling of having an urge to vomit)
Decreased appetite
Chest discomfort
Drug effect decreased
Drug ineffective
Early satiety (feeling full before completing a normal sized meal)
Headache (pain in head)
Hunger
Hypertension (high blood pressure)
Injection site bruising

What are the existing conditions these people have? *

Type 2 Diabetes: 11 people, 84.62%
Weight Loss: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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