Pravachol and Erythromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pravachol (pravastatin sodium) and Erythromycin (erythromycin). Common drug interactions include mitral valve incompetence among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Pravachol and Erythromycin. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Pravachol?

Pravachol has active ingredients of pravastatin sodium. It is often used in high blood cholesterol. eHealthMe is studying from 24,382 Pravachol users. Check the latest studies of Pravachol.

What is Erythromycin?

Erythromycin has active ingredients of erythromycin. It is often used in acne. eHealthMe is studying from 12,563 Erythromycin users. Check the latest studies of Erythromycin.

On Jul, 09, 2026

83 people who take Pravachol and Erythromycin together, and have interactions are studied.

Pravachol and Erythromycin drug interactions.

What are the common drug interactions of Pravachol and Erythromycin, by gender? *:

female:

Mitral valve incompetence (inefficient heart valve)
Pain
Aortic arteriosclerosis (hardening of the aortic arteries)
Cough
Heart rate increased
Injury
Myalgia (muscle pain)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Palpitations (feelings or sensations that your heart is pounding or racing)
Spinal osteoarthritis (joint cartilage loss in spine)

male:

Back pain
Arthralgia (joint pain)
Depression
Dysphonia (speech disorder attributable to a disorder of phonation)
Erectile dysfunction
Fall
Headache (pain in head)
Injury
Mitral valve incompetence (inefficient heart valve)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the common drug interactions of Pravachol and Erythromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Scar
Acute sinusitis
Anaemia (lack of blood)
Angiopathy (generic term for a disease of the blood vessels)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Arthropathy
Back pain
Bone disorder

10-19:

n/a

20-29:

n/a

30-39:

Anoxia (low oxygen)
Apnoea (suspension of external breathing)
Epistaxis (bleed from the nose)
Haemoglobin decreased
Hypotension (abnormally low blood pressure)
Lymphoma (cancer that begins in immune system cells)
Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)
Small intestinal perforation (hole in small intestine)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dizziness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Ventricular extrasystoles (premature cardiac contraction)

50-59:

Drug hypersensitivity
Headache (pain in head)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Myalgia (muscle pain)
Nephropathy (damage to or disease of a kidney)
Pain in limb
Peripheral swelling
Renal disorder (kidney disease)
Renal injury (kidney injury)
Chronic kidney disease

60+:

Diarrhoea
Dyspnoea (difficult or laboured respiration)
Palpitations (feelings or sensations that your heart is pounding or racing)
Spinal osteoarthritis (joint cartilage loss in spine)
Anxiety
Dry mouth
Heart rate irregular
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 25 people, 30.12%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 16.87%
Pain: 12 people, 14.46%
Infection: 9 people, 10.84%
Asthma: 8 people, 9.64%
High Blood Pressure: 6 people, 7.23%
Diabetes: 5 people, 6.02%
Anaemia (lack of blood): 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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