Prednisolone acetate and Trusopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisolone acetate (prednisolone acetate) and Trusopt (dorzolamide hydrochloride). Common drug interactions include blood sodium decreased among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisolone acetate and Trusopt. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisolone acetate?

Prednisolone acetate has active ingredients of prednisolone acetate. It is often used in uveitis. eHealthMe is studying from 8,151 Prednisolone acetate users. Check the latest studies of Prednisolone acetate.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 3,165 Trusopt users. Check the latest studies of Trusopt.



On Jul, 29, 2026

14 people who take Prednisolone acetate and Trusopt together, and have interactions are studied.

Prednisolone acetate and Trusopt drug interactions.

What are the common drug interactions of Prednisolone Acetate and Trusopt, by gender? *:

female:

  1. Blood sodium decreased
  2. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  3. Concussion (short loss of normal brain function in response to a head injury)
  4. Craniocerebral injury (injury to cranium and brain)
  5. Eye pain
  6. Haemorrhage (bleeding)
  7. Head injury
  8. Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
  9. Loss of consciousness
  10. Nerve root compression

male:

  1. Dehydration (dryness resulting from the removal of water)
  2. Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity)
  3. Eye irritation
  4. Eye pain
  5. Insomnia (sleeplessness)
  6. Intraocular pressure increased
  7. Iridocyclitis (inflammation of the iris and ciliary body of the eye)
  8. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  9. Ocular hyperaemia (an abnormally large amount of blood in eye)
  10. Ocular hypertension (intraocular pressure higher than normal)

What are the common drug interactions of Prednisolone Acetate and Trusopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
  2. Ureteric stenosis (abnormal narrowing or contraction of a duct or canal)

20-29:

  1. Drug ineffective

30-39:

n/a

40-49:

  1. Drug ineffective

50-59:

n/a

60+:

  1. Eye pain
  2. Visual impairment
  3. Dry eye (lack of adequate tears)
  4. Endophthalmitis (inflammation of the internal coats of the eye)
  5. Eye irritation
  6. Insomnia (sleeplessness)
  7. Intraocular pressure increased
  8. Iridocyclitis (inflammation of the iris and ciliary body of the eye)
  9. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  10. Ocular hyperaemia (an abnormally large amount of blood in eye)

What are the existing conditions these people have? *

  1. Intraocular Pressure Increased: 3 people, 21.43%
  2. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 21.43%
  3. Stress And Anxiety: 2 people, 14.29%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
  5. Eye Inflammation: 1 person, 7.14%
  6. High Blood Pressure: 1 person, 7.14%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 7.14%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.14%
  9. Eye Irritation: 1 person, 7.14%
  10. Dyspnea (difficult or laboured breathing): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prednisolone acetate and Trusopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisolone acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trusopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisolone acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trusopt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on prednisolone acetate and dorzolamide hydrochloride (the active ingredients of Prednisolone acetate and Trusopt, respectively), and Prednisolone acetate and Trusopt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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