Prednisone and Exforge hct drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Exforge hct (amlodipine; hydrochlorothiazide; valsartan). Common drug interactions include increased upper airway secretion among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Exforge hct. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Exforge hct?

Exforge hct has active ingredients of amlodipine; hydrochlorothiazide; valsartan. It is often used in high blood pressure. eHealthMe is studying from 4,095 Exforge hct users. Check the latest studies of Exforge hct.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

48 people who take Prednisone and Exforge hct together, and have interactions are studied.

Prednisone and Exforge hct drug interactions.

What are the common drug interactions of Prednisone and Exforge Hct, by gender? *:

female:

Increased upper airway secretion
Injection site erythema (redness at injection site)
Injection site haematoma (localized swelling filled with blood at injection site)
Joint crepitation
Malaise (a feeling of general discomfort or uneasiness)
Mobility decreased (ability to move is reduced)
Myalgia (muscle pain)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

male:

Arthralgia (joint pain)
Death
Chronic kidney disease
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Cytomegalovirus infection
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Drug ineffective
Dry eye (lack of adequate tears)

What are the common drug interactions of Prednisone and Exforge Hct, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Anxiety
Asthenia (weakness)
Chest pain
Crying
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Dizziness
Feeling of despair
Finger deformity (a deformed position of the finger)
Hypoaesthesia (reduced sense of touch or sensation)

50-59:

Joint swelling
Lacrimation increased
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Rhinorrhoea (watery mucus discharge from the nose)
Sinusitis (inflammation of sinus)
Staphylococcal infection (an infection with staphylococcus bacteria)
Upper-airway cough syndrome
Acne (skin problems that cause pimples)
Anxiety
Cardiac disorder

60+:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Arterial fibrosis (common cardiac arrhythmia)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest discomfort
Chest pain
Cough
Depressed mood
Diarrhoea
Discomfort

What are the existing conditions these people have? *

Pain: 6 people, 12.50%
Depression: 6 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.50%
Type 2 Diabetes: 5 people, 10.42%
High Blood Cholesterol: 5 people, 10.42%
Hypersensitivity: 5 people, 10.42%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 10.42%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 10.42%
Osteoporosis (bones weak and more likely to break): 4 people, 8.33%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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