Prednisone and Methylin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Methylin (methylphenidate hydrochloride). Common drug interactions include femoral arterial stenosis among females and drug abuse among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Methylin. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Methylin?

Methylin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,116 Methylin users. Check the latest studies of Methylin.

On Jul, 11, 2026

69 people who take Prednisone and Methylin together, and have interactions are studied.

Prednisone and Methylin drug interactions.

What are the common drug interactions of Prednisone and Methylin, by gender? *:

female:

Femoral arterial stenosis (narrowing of artery of femur bone)
Gingival ulceration (ulcer on gums)
Mitral valve incompetence (inefficient heart valve)
Sinus polyp (abnormal tissue growths that grow inside the nasal passages and sinuses)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Contusion (a type of hematoma of tissue in which capillaries)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Radiation injury (injuries are caused by radiation)
Scoliosis (a medical condition in which a person's spine is curved from side to side)

male:

Drug abuse
Chronic kidney disease
Osteoporosis (bones weak and more likely to break)
Pain
Quality of life decreased
Renal impairment (severely reduced kidney function)
Constipation
Disturbance in attention
Fatigue (feeling of tiredness)
Feeling jittery

What are the common drug interactions of Prednisone and Methylin, by age (0-1 to 60+)? *:

0-1:

Blood creatine phosphokinase increased
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Hyperthermia (body temperature greatly above normal)
Stomatitis (inflammation of mucous membrane of mouth)
Weight decreased

2-9:

n/a

10-19:

Headache (pain in head)
Insomnia (sleeplessness)
Lumbar puncture

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Loss of employment
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Quality of life decreased
Renal impairment (severely reduced kidney function)

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)

40-49:

Abdominal pain upper
Chronic kidney disease
Renal failure (kidney dysfunction)
Skin mass
Ulcer

50-59:

Vomiting
Limb injury
Anxiety
Chest pain
Depressed mood
Diarrhoea
Disturbance in attention
Dysphagia (a condition in which swallowing is difficult or painful)
Fear
Hypokalaemia (low potassium)

60+:

Asthenia (weakness)
Nausea (feeling of having an urge to vomit)
Carotid bruit (sound heard over the carotid artery area during auscultation)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Deformity (disfigurement)
Dementia (madness)
Depression

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 27 people, 39.13%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 21 people, 30.43%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 16 people, 23.19%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.70%
Depression: 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisone and Methylin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously