Prednisone and Temsirolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Temsirolimus (temsirolimus). Common drug interactions include dehydration among females and pneumocystis jiroveci pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Temsirolimus. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Temsirolimus?

Temsirolimus has active ingredients of temsirolimus. eHealthMe is studying from 3,573 Temsirolimus users. Check the latest studies of Temsirolimus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

62 people who take Prednisone and Temsirolimus together, and have interactions are studied.

Prednisone and Temsirolimus drug interactions.

What are the common drug interactions of Prednisone and Temsirolimus, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Pain
Bradycardia (abnormally slow heart action)
Dizziness
Hypoxia (low oxygen in tissues)
Lung infection
Metastases to lung (cancer spreads to lung)
Pleural effusion (water on the lungs)

male:

Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
Dyspnoea (difficult or laboured respiration)
Death
Fatigue (feeling of tiredness)
Neoplasm malignant (cancer tumour)
Anaemia (lack of blood)
Arthralgia (joint pain)
Hypotension (abnormally low blood pressure)
Injury
Pleural effusion (water on the lungs)

What are the common drug interactions of Prednisone and Temsirolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Respiratory failure (inadequate gas exchange by the respiratory system)
Acute respiratory distress syndrome
Bone marrow failure
Bradycardia (abnormally slow heart action)
Cough
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Epistaxis (bleed from the nose)
Fluid overload (too much fluid in the blood)
Hyperglycaemia (high blood sugar)

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hyperglycaemia (high blood sugar)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood creatinine increased
Blood phosphorus decreased
Blood triglycerides increased
Hypertension (high blood pressure)
International normalised ratio increased

40-49:

Cardiomyopathy (weakening of the heart muscle)
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Lung infection
Metastases to lung (cancer spreads to lung)
Nausea (feeling of having an urge to vomit)
Neutropenic infection (infection with less neutrophil numbers in blood)
Pain
Pleural effusion (water on the lungs)
Sudden death

50-59:

Influenza like illness
Injury
Insomnia (sleeplessness)
Intervertebral disc protrusion (spinal disc protrusion)
Lymphoedema (localized fluid retention and tissue swelling)
Metastases to bone (cancer spreads to bone)
Metastases to lung (cancer spreads to lung)
Mouth ulceration (mouth ulcers)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

60+:

Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
Gastric perforation (hole in stomach)
Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Oedema peripheral (superficial swelling)
Pain
Pneumonia
Proctalgia (pain in the rectum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Gastroenteritis (inflammation of stomach and intestine)

What are the existing conditions these people have? *

Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 13 people, 20.97%
High Blood Pressure: 10 people, 16.13%
Renal Cell Carcinoma (a kidney cancer): 8 people, 12.90%
Mantle Cell Lymphoma Refractory (relapsed cancer of lymphocytes, a type of white blood cell): 7 people, 11.29%
Prostate Cancer: 4 people, 6.45%
Pain: 4 people, 6.45%
High Blood Cholesterol: 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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