Pregabalin and Azactam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pregabalin (pregabalin) and Azactam (aztreonam). Common drug interactions include toxic epidermal necrolysis among females.

The phase IV clinical study analyzes what interactions people have when they take Pregabalin and Azactam. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.

What is Azactam?

Azactam has active ingredients of aztreonam. eHealthMe is studying from 1,044 Azactam users. Check the latest studies of Azactam.



On Jul, 30, 2026

12 people who take Pregabalin and Azactam together, and have interactions are studied.

Pregabalin and Azactam drug interactions.

What are the common drug interactions of Pregabalin and Azactam, by gender? *:

female:

  1. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  2. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  3. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  4. Pancreatitis acute (sudden inflammation of pancreas)
  5. Rash
  6. Vomiting
  7. Cardiac arrest
  8. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  9. Dermatitis infected (inflammation of the skin due to infection)
  10. Haemoglobin decreased

male:

n/a

What are the common drug interactions of Pregabalin and Azactam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  2. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
  3. Nausea (feeling of having an urge to vomit)
  4. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  5. Pancreatitis acute (sudden inflammation of pancreas)
  6. Vomiting
  7. Hidradenitis (chronic disease of a type of sweat gland)
  8. Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)

20-29:

n/a

30-39:

  1. Drug eruption (adverse drug reaction of the skin)
  2. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  3. Herpes virus infection
  4. Rash
  5. Dermatitis infected (inflammation of the skin due to infection)
  6. Human herpesvirus 6 infection
  7. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  8. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  9. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  10. Rash papular (redness with papule)

40-49:

n/a

50-59:

  1. Cardiac arrest
  2. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  3. Haemoglobin decreased
  4. Haemorrhage (bleeding)
  5. Lacunar infarction (a type of stroke)

60+:

  1. Hepatocellular injury (liver injury)

What are the existing conditions these people have? *

  1. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 2 people, 16.67%
  2. Agitation (state of anxiety or nervous excitement): 2 people, 16.67%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 8.33%
  5. Abscess (pus): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pregabalin and Azactam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azactam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pregabalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azactam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pregabalin and aztreonam (the active ingredients of Pregabalin and Azactam, respectively), and Pregabalin and Azactam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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