Pregabalin and Azulfidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pregabalin (pregabalin) and Azulfidine (sulfasalazine). Common drug interactions include back pain among females and fistula among males.

The phase IV clinical study analyzes what interactions people have when they take Pregabalin and Azulfidine. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.

What is Azulfidine?

Azulfidine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 7,997 Azulfidine users. Check the latest studies of Azulfidine.



On Jul, 19, 2026

40 people who take Pregabalin and Azulfidine together, and have interactions are studied.

Pregabalin and Azulfidine drug interactions.

What are the common drug interactions of Pregabalin and Azulfidine, by gender? *:

female:

  1. Back pain
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Blood cholesterol increased
  4. Body temperature increased
  5. Bone density decreased
  6. Breast cancer stage ii
  7. Breast cancer stage iii
  8. Burning sensation
  9. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  10. C-reactive protein increased

male:

  1. Fistula (an abnormal connection or passageway between two)
  2. Abdominal distension
  3. Peripheral swelling
  4. Swelling
  5. Vision blurred
  6. Abscess (pus)
  7. Anal fistula infection
  8. Infected fistula
  9. Pneumonia bacterial (pneumonia associated with bacterial infection)
  10. Post procedural complication

What are the common drug interactions of Pregabalin and Azulfidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Arthralgia (joint pain)
  2. Burning sensation
  3. Choking sensation (feeling of obstruction in respiratory system)
  4. Dizziness
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Headache (pain in head)
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Nausea (feeling of having an urge to vomit)
  9. Neck pain
  10. Respiratory distress (difficulty in breathing)

40-49:

  1. Abdominal pain upper
  2. Adverse drug reaction
  3. Adverse event
  4. Allergy to chemicals
  5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  6. Anti-cyclic citrullinated peptide antibody positive
  7. Anxiety
  8. Arthropathy
  9. Asthenia (weakness)
  10. Asthma

50-59:

  1. Fall
  2. Gastritis (inflammation of stomach)
  3. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  4. Respiratory tract infection viral
  5. Skin ulcer
  6. Depression
  7. Inflammation
  8. Blood glucose increased
  9. Arthralgia (joint pain)
  10. Drug ineffective

60+:

  1. Fistula (an abnormal connection or passageway between two)
  2. Arthralgia (joint pain)
  3. Infected fistula
  4. Pneumonia bacterial (pneumonia associated with bacterial infection)
  5. Post procedural complication
  6. Wound haemorrhage (bleeding wound)
  7. Pain in extremity
  8. Pyrexia (fever)
  9. Abscess jaw (tooth abscess or root abscess)
  10. Acute respiratory distress syndrome

What are the existing conditions these people have? *

  1. Ankylosing Spondylitis (type of arthritis affecting the spine): 12 people, 30.00%
  2. Pain: 9 people, 22.50%
  3. Insomnia (sleeplessness): 7 people, 17.50%
  4. Depression: 6 people, 15.00%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 12.50%
  6. Diabetes: 4 people, 10.00%
  7. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 10.00%
  8. Joint Pain: 3 people, 7.50%
  9. Psoriasis (immune-mediated disease that affects the skin): 3 people, 7.50%
  10. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pregabalin and Azulfidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azulfidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pregabalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azulfidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pregabalin and sulfasalazine (the active ingredients of Pregabalin and Azulfidine, respectively), and Pregabalin and Azulfidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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