Pregabalin and Cefotaxime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pregabalin (pregabalin) and Cefotaxime (cefotaxime sodium). Common drug interactions include acute generalised exanthematous pustulosis among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Pregabalin and Cefotaxime. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.

What is Cefotaxime?

Cefotaxime has active ingredients of cefotaxime sodium. eHealthMe is studying from 7,559 Cefotaxime users. Check the latest studies of Cefotaxime.



On Aug, 05, 2026

68 people who take Pregabalin and Cefotaxime together, and have interactions are studied.

Pregabalin and Cefotaxime drug interactions.

What are the common drug interactions of Pregabalin and Cefotaxime, by gender? *:

female:

  1. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  3. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Hallucination, visual (seeing things that aren't there)
  6. Nausea (feeling of having an urge to vomit)
  7. Subileus
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Pyrexia (fever)
  10. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

male:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Vestibular disorder (disorders of the body's balance (vestibular) system in the inner ear)
  3. Urinary tract infection
  4. Vomiting
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Eye movement disorder
  7. Hyporeflexia (a condition of below normal or absent reflexes)
  8. Leukopenia (less number of white blood cells in blood)
  9. Nausea (feeling of having an urge to vomit)
  10. Paresis (a condition of muscular weakness)

What are the common drug interactions of Pregabalin and Cefotaxime, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hepatocellular injury (liver injury)

30-39:

  1. Interstitial lung disease

40-49:

  1. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  2. Anaemia (lack of blood)
  3. Thrombocytopenia (decrease of platelets in blood)

50-59:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Nausea (feeling of having an urge to vomit)
  3. Pyrexia (fever)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  7. Acute respiratory failure
  8. Angiopathy (generic term for a disease of the blood vessels)
  9. Atelectasis (partial or complete collapse of the lung)
  10. Bacterial test positive

60+:

  1. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Subileus
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Balance disorder
  6. Nausea (feeling of having an urge to vomit)
  7. Urinary tract infection
  8. Vomiting
  9. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  10. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

What are the existing conditions these people have? *

  1. Pain: 22 people, 32.35%
  2. High Blood Pressure: 13 people, 19.12%
  3. Neuralgia (pain in one or more nerves): 9 people, 13.24%
  4. Nausea (feeling of having an urge to vomit): 9 people, 13.24%
  5. Multiple Myeloma (cancer of the plasma cells): 9 people, 13.24%
  6. Arthritis Infective (purulent invasion of a joint by an infectious agent which produces arthritis): 7 people, 10.29%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 8.82%
  8. Anaemia (lack of blood): 5 people, 7.35%
  9. Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 5.88%
  10. Diabetes: 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pregabalin and Cefotaxime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pregabalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cefotaxime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pregabalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefotaxime and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pregabalin and cefotaxime sodium (the active ingredients of Pregabalin and Cefotaxime, respectively), and Pregabalin and Cefotaxime (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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