Pregabalin and Tobramycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pregabalin (pregabalin) and Tobramycin (tobramycin). Common drug interactions include surgery among females and aplastic anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Pregabalin and Tobramycin. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.

What is Tobramycin?

Tobramycin has active ingredients of tobramycin. It is often used in cystic fibrosis. eHealthMe is studying from 3,579 Tobramycin users. Check the latest studies of Tobramycin.

On Aug, 06, 2026

35 people who take Pregabalin and Tobramycin together, and have interactions are studied.

Pregabalin and Tobramycin drug interactions.

What are the common drug interactions of Pregabalin and Tobramycin, by gender? *:

female:

Surgery
Anxiety
Bone density decreased
Diarrhoea
Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)

male:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Febrile neutropenia (fever with reduced white blood cells)
Localised infection (infection at the single location)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasal inflammation (inflammation of nose)
Pain in extremity
Productive cough
Wheezing (a high-pitched whistling sound made while you breath)
Mucosal inflammation (infection of mucous membrane)
Oedema peripheral (superficial swelling)

What are the common drug interactions of Pregabalin and Tobramycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Febrile neutropenia (fever with reduced white blood cells)
Mucosal inflammation (infection of mucous membrane)
Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Bone density decreased
Emotional distress
Fatigue (feeling of tiredness)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Renal impairment (severely reduced kidney function)

50-59:

Surgery
Chronic kidney disease
Bone density decreased
Fall
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Tooth fracture
Tooth loss
Wrist fracture

60+:

Oedema peripheral (superficial swelling)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Amputation
Back pain
Blood potassium decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Death
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Cytomegalovirus Infection: 10 people, 28.57%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 14.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 14.29%
Drowsiness: 4 people, 11.43%
Hiv Infection: 3 people, 8.57%
Headache (pain in head): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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