Pregabalin and Tpn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pregabalin (pregabalin) and Tpn (niacinamide; pyridoxine hydrochloride; tyrosine). Common drug interactions include pneumonia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Pregabalin and Tpn. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.

What is Tpn?

Tpn has active ingredients of niacinamide; pyridoxine hydrochloride; tyrosine. eHealthMe is studying from 1,581 Tpn users. Check the latest studies of Tpn.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

15 people who take Pregabalin and Tpn together, and have interactions are studied.

What are the common drug interactions of Pregabalin and Tpn, by gender? *:

female:

Pneumonia
Road traffic accident
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Tendon disorder (disease of tendon)
Urinary retention (the inability to completely or partially empty the bladder)
Urinary tract infection
Wrist fracture
Weight fluctuation
Diarrhoea
Frequent bowel movements

male:

Abdominal pain
Abnormal faeces (abnormal stool)
Large intestinal obstruction
Retching (strong involuntary effort to vomit)
Vomiting
Weight increased
Eating disorder
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cholecystitis acute (rapid infection of gallbladder)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the common drug interactions of Pregabalin and Tpn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)

20-29:

Gastric infection (infection of stomach)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Post procedural drainage
Swelling face
Abdominal pain
Abnormal faeces (abnormal stool)
Diarrhoea
Dizziness

30-39:

n/a

40-49:

Nausea (feeling of having an urge to vomit)
Weight decreased
Diarrhoea
Abdominal pain
Abnormal faeces (abnormal stool)
Biliary colic
Defaecation urgency (a sudden compelling urge to defecate)
Eructation (release of gas from the digestive tract)
Flatulence (flatus expelled through the anus)
Hunger

50-59:

n/a

60+:

Abdominal distension
Abdominal pain lower
Chest pain
Chills (felling of cold)
Cough
Decreased appetite
Depression
Diarrhoea
Dizziness
Drug ineffective

What are the existing conditions these people have? *

Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 7 people, 46.67%
Functional Gastrointestinal Disorder (functional problem in separate organs of gastrointestinal system): 4 people, 26.67%
Nausea (feeling of having an urge to vomit): 3 people, 20.00%
Depression: 3 people, 20.00%
Gastroenteritis (inflammation of stomach and intestine): 2 people, 13.33%
Colitis (inflammation of colon): 2 people, 13.33%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 13.33%
Diarrhea: 2 people, 13.33%
Abdominal Discomfort: 2 people, 13.33%
Neuropathy Peripheral (surface nerve damage): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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