Pregabalin and Uptravi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pregabalin (pregabalin) and Uptravi (selexipag). Common drug interactions include arthritis bacterial among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Pregabalin and Uptravi. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.

What is Uptravi?

Uptravi has active ingredients of selexipag. eHealthMe is studying from 26,576 Uptravi users. Check the latest studies of Uptravi.

On Jul, 23, 2026

39 people who take Pregabalin and Uptravi together, and have interactions are studied.

Pregabalin and Uptravi drug interactions.

What are the common drug interactions of Pregabalin and Uptravi, by gender? *:

female:

Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Interstitial lung disease
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Asthenia (weakness)
Disability
Dizziness
Emotional distress
Feeding disorder (when children refuse to eat certain food groups)
Feeling cold

male:

Dyspnoea (difficult or laboured respiration)
Back pain
Erythema (redness of the skin)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Gout (uric acid crystals building up in the body)
Haematoma (collection of blood outside the blood vessels)
Haemorrhage (bleeding)
Headache (pain in head)
Hypertension (high blood pressure)
Hypokalaemia (low potassium)

What are the common drug interactions of Pregabalin and Uptravi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Mastoiditis (infection of mastoid bone)
Fungaemia (fungi circulate in the blood)
Pulmonary oedema (fluid accumulation in the lungs)
Viral infection

40-49:

Device dislocation
Fluid overload (too much fluid in the blood)
Fluid retention (an abnormal accumulation of fluid in the blood)
Pulmonary hypertension (increase in blood pressure in the lung artery)

50-59:

Haematoma (collection of blood outside the blood vessels)
Haemoglobin decreased
Haemorrhage (bleeding)
Hypertension (high blood pressure)
Hypokalaemia (low potassium)
Joint range of motion decreased (disease of joint movement)
Joint swelling
Left ventricular failure (left ventricle fails to contract forcefully)
Liver transplant
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)

60+:

Dyspnoea (difficult or laboured respiration)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Pericardial effusion (fluid around the heart)
Rectal haemorrhage (bleeding from anus)
Right ventricular failure (right half of the heart fails to work)
Headache (pain in head)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Chest discomfort
Dehydration (dryness resulting from the removal of water)
Kidney infection

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 32 people, 82.05%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.69%
Stress And Anxiety: 2 people, 5.13%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 2 people, 5.13%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.13%
Pain: 2 people, 5.13%
Diarrhea: 2 people, 5.13%
Depression: 2 people, 5.13%
Connective Tissue Disorder (any disease that has the connective tissues of the body): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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