Premarin and Bextra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Premarin (estrogens, conjugated) and Bextra (valdecoxib). Common drug interactions include chest pain among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Premarin and Bextra. It is created by eHealthMe based on reports of 437 people who take the same drugs from the FDA, and is updated regularly.
What is Premarin?
Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.
What is Bextra?
Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.
437 people who take Premarin and Bextra together, and have interactions are studied.

What are the common drug interactions of Premarin and Bextra, by gender? *
What are the common drug interactions of Premarin and Bextra, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Premarin and Bextra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Premarin and Bextra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Premarin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bextra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Premarin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bextra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on estrogens, conjugated and valdecoxib (the active ingredients of Premarin and Bextra, respectively), and Premarin and Bextra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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