Premarin and Ciclopirox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Premarin (estrogens, conjugated) and Ciclopirox (ciclopirox). Common drug interactions include chronic kidney disease among females.

The phase IV clinical study analyzes what interactions people have when they take Premarin and Ciclopirox. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

What is Ciclopirox?

Ciclopirox has active ingredients of ciclopirox. eHealthMe is studying from 2,646 Ciclopirox users. Check the latest studies of Ciclopirox.

On Aug, 04, 2026

24 people who take Premarin and Ciclopirox together, and have interactions are studied.

Premarin and Ciclopirox drug interactions.

What are the common drug interactions of Premarin and Ciclopirox, by gender? *:

female:

Chronic kidney disease
Diarrhoea
Foot fracture
Gastric cancer (stomach cancer)
Hypertension (high blood pressure)
Lymphoedema (localized fluid retention and tissue swelling)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Nerve injury
Pain in extremity

male:

n/a

What are the common drug interactions of Premarin and Ciclopirox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Depression
Diarrhoea

30-39:

n/a

40-49:

n/a

50-59:

Agitation (state of anxiety or nervous excitement)
Anxiety
Bruxism (habitual grinding of the teeth, typically during sleep)
Hypertension (high blood pressure)
Swelling
Blindness
Decreased appetite
Faeces discoloured
Frequent bowel movements
Headache (pain in head)

60+:

Chronic kidney disease
Abscess (pus)
Retching (strong involuntary effort to vomit)
Vomiting
Diarrhoea
Anxiety
Application site pain
Arthralgia (joint pain)
Asthma
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 37.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 29.17%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 29.17%
High Blood Pressure: 6 people, 25.00%
Pain: 5 people, 20.83%
Depression: 4 people, 16.67%
Sleep Disorder: 4 people, 16.67%
Stress And Anxiety: 4 people, 16.67%
Hypersensitivity: 4 people, 16.67%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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