Premarin and Golytely drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Premarin (estrogens, conjugated) and Golytely (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous). Common drug interactions include anxiety among females.

The phase IV clinical study analyzes what interactions people have when they take Premarin and Golytely. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

What is Golytely?

Golytely has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous. eHealthMe is studying from 907 Golytely users. Check the latest studies of Golytely.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 04, 2026

11 people who take Premarin and Golytely together, and have interactions are studied.

Premarin and Golytely drug interactions.

What are the common drug interactions of Premarin and Golytely, by gender? *:

female:

  1. Anxiety
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Gastritis (inflammation of stomach)
  4. Gastroduodenitis (an inflammation of the mucous membrane of the stomach and duodenum)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Hypertension (high blood pressure)
  7. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  8. Nausea (feeling of having an urge to vomit)
  9. Palpitations (feelings or sensations that your heart is pounding or racing)
  10. Urinary tract infection

male:

n/a

What are the common drug interactions of Premarin and Golytely, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Constipation
  2. Depression
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Suicide attempt
  5. Therapeutic response unexpected

60+:

  1. Anxiety
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  3. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  4. Nausea (feeling of having an urge to vomit)
  5. Pain
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Urinary tract infection
  8. Adverse drug reaction
  9. Arteriosclerosis (thickening and hardening of arteries)
  10. Bacterial infection

What are the existing conditions these people have? *

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 18.18%
  2. Cardiac Disorder: 2 people, 18.18%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 18.18%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 18.18%
  5. Infection: 1 person, 9.09%
  6. Depression: 1 person, 9.09%
  7. Gastric Ulcer (stomach ulcer): 1 person, 9.09%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
  9. High Blood Pressure: 1 person, 9.09%
  10. Hiv Infection: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Premarin and Golytely?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Premarin and Golytely:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Premarin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Golytely:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Premarin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Golytely and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on estrogens, conjugated and polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous (the active ingredients of Premarin and Golytely, respectively), and Premarin and Golytely (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: