Premarin and Methoxsalen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Premarin (estrogens, conjugated) and Methoxsalen (methoxsalen). Common drug interactions include dysphagia among females.
The phase IV clinical study analyzes what interactions people have when they take Premarin and Methoxsalen. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Premarin?
Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.
What is Methoxsalen?
Methoxsalen has active ingredients of methoxsalen. eHealthMe is studying from 153 Methoxsalen users. Check the latest studies of Methoxsalen.
12 people who take Premarin and Methoxsalen together, and have interactions are studied.

What are the common drug interactions of Premarin and Methoxsalen, by gender? *:
female:
- Dysphagia (a condition in which swallowing is difficult or painful)
- Drug intolerance (drug sensitivity)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Febrile neutropenia (fever with reduced white blood cells)
- Flat affect (absence of emotional response to a situation)
- Iron deficiency anaemia
- Leukocytosis (increased white blood cells)
- Neuropathy peripheral (surface nerve damage)
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
male:
n/a
What are the common drug interactions of Premarin and Methoxsalen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Cardiac failure
- Drug intolerance (drug sensitivity)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Vomiting
30-39:
- Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
- Pulmonary embolism (blockage of the main artery of the lung)
- Flat affect (absence of emotional response to a situation)
- Iron deficiency anaemia
- Leukocytosis (increased white blood cells)
- Neuropathy peripheral (surface nerve damage)
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
- Nipple disorder (disease of nipple)
- Osteonecrosis (death of bone)
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
40-49:
n/a
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 9 people, 75.00%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 9 people, 75.00%
- Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 3 people, 25.00%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 8.33%
- Sleep Disorder: 1 person, 8.33%
- Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 8.33%
- Oedema (fluid collection in tissue): 1 person, 8.33%
- Nausea (feeling of having an urge to vomit): 1 person, 8.33%
- Infection: 1 person, 8.33%
- Immunodeficiency Disorders: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Premarin and Methoxsalen?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Premarin (99,630 reports)
- Methoxsalen (153 reports)
Browse all drug interactions of Premarin and Methoxsalen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Premarin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Methoxsalen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Premarin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methoxsalen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on estrogens, conjugated and methoxsalen (the active ingredients of Premarin and Methoxsalen, respectively), and Premarin and Methoxsalen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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