Premarin and Rowasa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Premarin (estrogens, conjugated) and Rowasa (mesalamine). Common drug interactions include abdominal pain among females.

The phase IV clinical study analyzes what interactions people have when they take Premarin and Rowasa. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

What is Rowasa?

Rowasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 943 Rowasa users. Check the latest studies of Rowasa.



On Jul, 28, 2026

13 people who take Premarin and Rowasa together, and have interactions are studied.

Premarin and Rowasa drug interactions.

What are the common drug interactions of Premarin and Rowasa, by gender? *:

female:

  1. Abdominal pain
  2. Diarrhoea
  3. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Abnormal faeces (abnormal stool)
  6. Acute respiratory distress syndrome
  7. Anaemia (lack of blood)
  8. Arthralgia (joint pain)
  9. Bradycardia (abnormally slow heart action)
  10. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

male:

n/a

What are the common drug interactions of Premarin and Rowasa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Pain

50-59:

  1. Diarrhoea
  2. Flatulence (flatus expelled through the anus)
  3. Headache (pain in head)
  4. Pain

60+:

  1. Abdominal discomfort
  2. Abdominal pain
  3. Bradycardia (abnormally slow heart action)
  4. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  5. Collapse (sudden functional breakdown)
  6. Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Drug ineffective
  9. Dyspnoea (difficult or laboured respiration)
  10. Face oedema (swelling of face)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 30.77%
  2. Sleep Disorder: 2 people, 15.38%
  3. Diarrhea: 2 people, 15.38%
  4. Chest Pain: 2 people, 15.38%
  5. Abdominal Pain: 2 people, 15.38%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  7. Anaemia Of Chronic Disease: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Premarin and Rowasa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Premarin and Rowasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Premarin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rowasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Premarin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rowasa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on estrogens, conjugated and mesalamine (the active ingredients of Premarin and Rowasa, respectively), and Premarin and Rowasa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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