Premarin and Tambocor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Premarin (estrogens, conjugated) and Tambocor (flecainide acetate). Common drug interactions include dyspnoea among females.

The phase IV clinical study analyzes what interactions people have when they take Premarin and Tambocor. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

What is Tambocor?

Tambocor has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,621 Tambocor users. Check the latest studies of Tambocor.

On Jul, 26, 2026

42 people who take Premarin and Tambocor together, and have interactions are studied.

Premarin and Tambocor drug interactions.

What are the common drug interactions of Premarin and Tambocor, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Diarrhoea
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Cervix inflammation
Cluster headache (one-sided head pain with tearing)

male:

n/a

What are the common drug interactions of Premarin and Tambocor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Migraine (headache)
Anaphylactic reaction (serious allergic reaction)
Drug hypersensitivity

50-59:

Nervousness
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Skin discolouration (change of skin colour)
Skin ulcer
Sweating increased (excess sweating)
Tearfulness (excess tearing)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Pain
Scar

60+:

Breast cancer
Diarrhoea
Cervix inflammation
Chest pain
Cluster headache (one-sided head pain with tearing)
Decreased immune responsiveness
Depression
Dihydrotestosterone decreased
Dry skin
Dyslipidaemia (abnormal amount of lipids)

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 9.52%
Stress And Anxiety: 3 people, 7.14%
Pain: 3 people, 7.14%
Arrhythmias (irregular heartbeat): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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