Prempro and Corgard drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prempro (estrogens, conjugated; medroxyprogesterone acetate) and Corgard (nadolol). Common drug interactions include pulmonary embolism among females and feeling hot among males.

The phase IV clinical study analyzes what interactions people have when they take Prempro and Corgard. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Prempro?

Prempro has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. It is often used in menopause. eHealthMe is studying from 42,950 Prempro users. Check the latest studies of Prempro.

What is Corgard?

Corgard has active ingredients of nadolol. It is often used in high blood pressure. eHealthMe is studying from 3,342 Corgard users. Check the latest studies of Corgard.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

38 people who take Prempro and Corgard together, and have interactions are studied.

What are the common drug interactions of Prempro and Corgard, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Skin ulcer
Acne (skin problems that cause pimples)
Breast cancer
Breast pain
Breast swelling
Cardiac failure congestive
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea

male:

Feeling hot
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the common drug interactions of Prempro and Corgard, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pulmonary embolism (blockage of the main artery of the lung)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

50-59:

Cardiac failure congestive
Cardiogenic shock (inadequate circulation of blood)
Cardiomegaly (increased size of heart than normal)
Chest discomfort
Chest pain
Collapse (sudden functional breakdown)
Conjunctivitis (pink eye)
Cough
Crest syndrome (thick, dry and fibrous skin)
Decreased appetite

60+:

Breast cancer female
Ovarian cancer (cancer of ovary)
Anxiety disorder
Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)
Bone density decreased
Bone pain
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast cancer in situ
Breast fibrosis (the thickening and scarring of connective tissue, usually as a result of injury in breast)
Breast hyperplasia (accumulation of abnormal cells in a breast duct)

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 7.89%
Mitral Valve Prolapse (heart's mitral valve doesn't work well): 3 people, 7.89%
Osteoporosis (bones weak and more likely to break): 2 people, 5.26%
Migraine (headache): 2 people, 5.26%
Menopausal Symptoms: 2 people, 5.26%
Hypersensitivity: 2 people, 5.26%
Hot Flush (sudden feelings of heat): 2 people, 5.26%
Cardiac Disorder: 2 people, 5.26%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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