Prevacid and Purinethol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prevacid (lansoprazole) and Purinethol (mercaptopurine). Common drug interactions include drug hypersensitivity among females and adverse drug reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Prevacid and Purinethol. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Prevacid?

Prevacid has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 130,714 Prevacid users. Check the latest studies of Prevacid.

What is Purinethol?

Purinethol has active ingredients of mercaptopurine. It is often used in ulcerative colitis. eHealthMe is studying from 3,810 Purinethol users. Check the latest studies of Purinethol.

On Jul, 15, 2026

29 people who take Prevacid and Purinethol together, and have interactions are studied.

Prevacid and Purinethol drug interactions.

What are the common drug interactions of Prevacid and Purinethol, by gender? *:

female:

Drug hypersensitivity
Emotional distress
Hospitalisation
Inflammatory bowel disease
Injection site bruising
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site tenderness
Intestinal obstruction

male:

Adverse drug reaction
Arthralgia (joint pain)
Gastric haemorrhage (bleeding stomach)
Hydronephrosis (water inside the kidney)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephrolithiasis (calculi in the kidneys)
Renal failure acute (rapid kidney dysfunction)
Retroperitoneal haematoma (blood clot between the peritoneum and the posterior abdominal wall)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Prevacid and Purinethol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Febrile neutropenia (fever with reduced white blood cells)

10-19:

n/a

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Inflammatory bowel disease
Intestinal obstruction
Liver abscess (pus in liver)
Nausea (feeling of having an urge to vomit)
Vomiting

30-39:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blindness transient (sudden loss of vision)
Blood alkaline phosphatase increased
Drug hypersensitivity
Hepatitis acute
Leukocytosis (increased white blood cells)
Mobility decreased (ability to move is reduced)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Pharyngitis (inflammation of the pharynx, causing a sore throat)

40-49:

Adverse drug reaction
Ankle fracture
Anxiety
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Application site reaction
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back injury
Back pain
Bone disorder
Calcium deficiency (lack of calcium)

50-59:

Arthralgia (joint pain)
Bradycardia (abnormally slow heart action)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pruritus generalised (generalized itching)
Rash

60+:

Arthralgia (joint pain)
Diarrhoea
Hepatitis acute
Hydronephrosis (water inside the kidney)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephrolithiasis (calculi in the kidneys)
Renal failure acute (rapid kidney dysfunction)
Retroperitoneal haematoma (blood clot between the peritoneum and the posterior abdominal wall)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 13.79%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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