Previfem and Prozac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Previfem (ethinyl estradiol; norgestimate) and Prozac (fluoxetine hydrochloride). Common drug interactions include acute psychosis among females.

The phase IV clinical study analyzes what interactions people have when they take Previfem and Prozac. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Previfem?

Previfem has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 602 Previfem users. Check the latest studies of Previfem.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.



On Jul, 06, 2026

12 people who take Previfem and Prozac together, and have interactions are studied.

Previfem and Prozac drug interactions.

What are the common drug interactions of Previfem and Prozac, by gender? *:

female:

  1. Acute psychosis (period of mentally unstable behaviour)
  2. Hypertension (high blood pressure)
  3. Weight increased
  4. Insomnia (sleeplessness)
  5. Affect lability (emotional incontinence)
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Asthenia (weakness)
  8. Ataxia (loss of full control of bodily movements)
  9. Back pain
  10. Blindness

male:

n/a

What are the common drug interactions of Previfem and Prozac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Acute psychosis (period of mentally unstable behaviour)
  2. Hypertension (high blood pressure)
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Respiratory syncytial virus infection (viral disease of respiratory system)
  5. Somnambulism (sleep walking)
  6. Headache (pain in head)
  7. Weight increased
  8. Fatigue (feeling of tiredness)
  9. Insomnia (sleeplessness)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 91.67%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 50.00%
  3. Drowsiness: 4 people, 33.33%
  4. Stress And Anxiety: 1 person, 8.33%
  5. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 8.33%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
  7. Migraine (headache): 1 person, 8.33%
  8. Irritable Bowel Syndrome: 1 person, 8.33%
  9. Insomnia (sleeplessness): 1 person, 8.33%
  10. Headache (pain in head): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Previfem and Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Previfem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Previfem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate and fluoxetine hydrochloride (the active ingredients of Previfem and Prozac, respectively), and Previfem and Prozac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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