Prevpac and Hydroxyzine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Prevpac (amoxicillin; clarithromycin; lansoprazole) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include renal failure among females and abdominal discomfort among males.
The phase IV clinical study analyzes what interactions people have when they take Prevpac and Hydroxyzine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Prevpac?
Prevpac has active ingredients of amoxicillin; clarithromycin; lansoprazole. It is often used in helicobacter pylori. eHealthMe is studying from 758 Prevpac users. Check the latest studies of Prevpac.
What is Hydroxyzine?
Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,070 Hydroxyzine users. Check the latest studies of Hydroxyzine.
16 people who take Prevpac and Hydroxyzine together, and have interactions are studied.

What are the common drug interactions of Prevpac and Hydroxyzine, by gender? *:
female:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Emotional distress
- Pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Asthenia (weakness)
- Bone density decreased
- Fatigue (feeling of tiredness)
- Osteopenia (a condition where bone mineral density is lower than normal)
male:
- Abdominal discomfort
- Abdominal pain upper
- Eosinophil count increased
- Excessive masturbation
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Hepatic fibrosis (scarring process that represents the liver's response to injury)
- Hepatomegaly (abnormal enlargement of the liver)
- Hypersexuality
What are the common drug interactions of Prevpac and Hydroxyzine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Emotional distress
- General physical health deterioration (weak health status)
- Injury
- Pain
- Pulmonary embolism (blockage of the main artery of the lung)
30-39:
- Abdominal discomfort
- Abdominal pain upper
- Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
- Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
- Compulsive sexual behaviour (unable to manage his/her sexual behaviour)
- Cough
- Drug hypersensitivity
- Dry mouth
- Dyspepsia (indigestion)
- Eating disorder
40-49:
- Fatigue (feeling of tiredness)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Renal impairment (severely reduced kidney function)
- Chronic kidney disease
- Hyperkalaemia (damage to or disease of the kidney)
- Renal tubular necrosis (death of kidney tubules)
- Renal failure (kidney dysfunction)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
50-59:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
60+:
- Chronic kidney disease
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 43.75%
- Pain: 6 people, 37.50%
- Depression: 5 people, 31.25%
- High Blood Pressure: 4 people, 25.00%
- High Blood Cholesterol: 4 people, 25.00%
- Cardiac Disorder: 4 people, 25.00%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 18.75%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 18.75%
- Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 3 people, 18.75%
- Gastric Ulcer (stomach ulcer): 3 people, 18.75%
* Approximation only. Some reports may have incomplete information.
Do you take Prevpac and Hydroxyzine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Prevpac (758 reports)
- Hydroxyzine (54,070 reports)
Browse all drug interactions of Prevpac and Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Prevpac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prevpac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyzine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on amoxicillin; clarithromycin; lansoprazole and hydroxyzine hydrochloride (the active ingredients of Prevpac and Hydroxyzine, respectively), and Prevpac and Hydroxyzine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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