Prezista and Nitroglycerin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prezista (darunavir ethanolate) and Nitroglycerin (nitroglycerin). Common drug interactions include crying among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prezista and Nitroglycerin. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Prezista?

Prezista has active ingredients of darunavir ethanolate. It is often used in hiv infection. eHealthMe is studying from 12,363 Prezista users. Check the latest studies of Prezista.

What is Nitroglycerin?

Nitroglycerin has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 52,884 Nitroglycerin users. Check the latest studies of Nitroglycerin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

66 people who take Prezista and Nitroglycerin together, and have interactions are studied.

Prezista and Nitroglycerin drug interactions.

What are the common drug interactions of Prezista and Nitroglycerin, by gender? *:

female:

Crying
Death
Renal atrophy (wasting of kidney)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Restlessness (not able to rest)
Suicidal ideation
Thrombosis (formation of a blood clot inside a blood vessel)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Anger

male:

Chronic kidney disease
Emotional distress
Fatigue (feeling of tiredness)
Renal impairment (severely reduced kidney function)
Osteonecrosis (death of bone)
Gait disturbance
Decreased activity
Mobility decreased (ability to move is reduced)
Quality of life decreased
Blood creatinine increased

What are the common drug interactions of Prezista and Nitroglycerin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Crying
Depression
Emotional distress
Pain
Renal atrophy (wasting of kidney)
Renal impairment (severely reduced kidney function)
Restlessness (not able to rest)

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Back pain
Bone density decreased
Chronic kidney disease
Dysstasia (difficulty in standing)
Emotional distress
Fatigue (feeling of tiredness)
Gait disturbance

40-49:

Chronic kidney disease
Emotional distress
Osteonecrosis (death of bone)
Pain
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Blood creatinine increased

50-59:

Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
Rib fracture
Skeletal injury (bone and supporting muscle injury)
Spinal compression fracture (fracture due to spinal compression on bone)
Spinal fracture (fracture in one of vertebrae)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Tooth loss
Vitamin d decreased
Chronic kidney disease
Anxiety

60+:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Insomnia (sleeplessness)
Multiple fractures
Nephrolithiasis (calculi in the kidneys)
Osteopenia (a condition where bone mineral density is lower than normal)
Psychotic disorder
Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

High Blood Pressure: 20 people, 30.30%
Pain: 17 people, 25.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 22.73%
Depression: 13 people, 19.70%
Insomnia (sleeplessness): 12 people, 18.18%
Bacterial Infection: 11 people, 16.67%
Asthma: 9 people, 13.64%
Stress And Anxiety: 9 people, 13.64%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 13.64%
High Blood Cholesterol: 8 people, 12.12%

* Approximation only. Some reports may have incomplete information.

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