Prialt and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prialt (ziconotide) and Ibu (ibuprofen). Common drug interactions include multiple sclerosis relapse among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Prialt and Ibu. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Prialt?

Prialt has active ingredients of ziconotide. It is often used in pain. eHealthMe is studying from 2,665 Prialt users. Check the latest studies of Prialt.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

On Aug, 02, 2026

29 people who take Prialt and Ibu together, and have interactions are studied.

What are the common drug interactions of Prialt and Ibu, by gender? *:

female:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Swelling
Cerebrospinal fluid leakage
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Nystagmus (a condition of involuntary eye movement)
Ophthalmoplegia (a paralysis or weakness of one or more of the muscles that control eye movement)
Pseudomeningocele (abnormal collection of cerebrospinal fluid)
Aphasia (damage to the parts of the brain that control language)
Drug ineffective
Hallucination, auditory (perceiving sounds without auditory stimulus)

male:

Diarrhoea
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Hot flush (sudden feelings of heat)
Implant site extravasation
Nausea (feeling of having an urge to vomit)
Vomiting projectile
Amaurosis (partial or total blindness without visible change in the eye)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anal haemorrhage
Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Prialt and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cerebrospinal fluid leakage
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Pseudomeningocele (abnormal collection of cerebrospinal fluid)
Swelling

30-39:

Aphasia (damage to the parts of the brain that control language)
Drug ineffective
Hallucination, auditory (perceiving sounds without auditory stimulus)
Insomnia (sleeplessness)
Memory impairment
Mood altered (changes in mood)
Muscle twitching

40-49:

Myelitis (infection or the inflammation of white matter or gray matter of spinal cord which is a part of central nervous system)
Paraplegia (paralysis of the legs and lower body)
Balance disorder
Catheter site related reaction
Dysstasia (difficulty in standing)
Fall
Gait disturbance
Joint lock
Joint stiffness
Mobility decreased (ability to move is reduced)

50-59:

Confusional state
Asthenia (weakness)
Diplopia (double vision)
Dizziness
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
Hot flush (sudden feelings of heat)
Nausea (feeling of having an urge to vomit)
Vomiting projectile
Amaurosis (partial or total blindness without visible change in the eye)
Anal haemorrhage

60+:

Diarrhoea
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Sinusitis (inflammation of sinus)
Swelling
Vomiting
Back disorder
Spinal fusion surgery
Cardiac disorder
Dyspnoea (difficult or laboured respiration)
Hypersensitivity

What are the existing conditions these people have? *

Post Laminectomy Syndrome: 8 people, 27.59%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 17.24%
Spinal Pain (pain in spine): 2 people, 6.90%
Muscle Spasms (muscle contraction): 2 people, 6.90%
Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 6.90%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 6.90%
Gait Disturbance: 2 people, 6.90%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 2 people, 6.90%
Back Pain: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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