Prilosec otc and Hydroxyurea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec otc (omeprazole magnesium) and Hydroxyurea (hydroxyurea). Common drug interactions include constipation among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec otc and Hydroxyurea. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec otc?

Prilosec otc has active ingredients of omeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 38,394 Prilosec otc users. Check the latest studies of Prilosec otc.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

11 people who take Prilosec otc and Hydroxyurea together, and have interactions are studied.

Prilosec otc and Hydroxyurea drug interactions.

What are the common drug interactions of Prilosec Otc and Hydroxyurea, by gender? *:

female:

Constipation
Essential hypertension (primary hypertension)
Renal injury (kidney injury)
Skin infection
Urinary tract infection
Chronic kidney disease
Cerebral haematoma (collection of blood in brain)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Nephrogenic anaemia (anaemia due to kidney disease)
Death
Renal cancer (cancer of kidney)
Renal cancer metastatic (cancer of kidney spreads to other part)
Renal injury (kidney injury)

What are the common drug interactions of Prilosec Otc and Hydroxyurea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Urinary tract infection
Chronic kidney disease
Cerebral haematoma (collection of blood in brain)
Constipation
Essential hypertension (primary hypertension)
Skin infection

60+:

Chronic kidney disease
Death
Renal cancer (cancer of kidney)
Renal cancer metastatic (cancer of kidney spreads to other part)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Indigestion: 4 people, 36.36%
Gastric Ulcer (stomach ulcer): 4 people, 36.36%
Depression: 4 people, 36.36%
Pain: 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
High Blood Cholesterol: 3 people, 27.27%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 27.27%
Bone Marrow Disorder: 3 people, 27.27%
Oedema (fluid collection in tissue): 1 person, 9.09%
Infection: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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