Prilosec and Amnesteem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Amnesteem (isotretinoin). Common drug interactions include chronic kidney disease among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Amnesteem. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

What is Amnesteem?

Amnesteem has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 7,344 Amnesteem users. Check the latest studies of Amnesteem.



On Jul, 19, 2026

24 people who take Prilosec and Amnesteem together, and have interactions are studied.

Prilosec and Amnesteem drug interactions.

What are the common drug interactions of Prilosec and Amnesteem, by gender? *:

female:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal impairment (severely reduced kidney function)
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  5. Renal disorder (kidney disease)
  6. Anxiety
  7. Death
  8. Suicidal ideation
  9. Adverse drug reaction
  10. Arthralgia (joint pain)

male:

  1. Arthralgia (joint pain)
  2. Anger
  3. Blood triglycerides increased
  4. Chapped lips (cracking, fissuring, and peeling of the skin f lip)
  5. Diarrhoea
  6. Nausea (feeling of having an urge to vomit)
  7. Costochondritis (chest wall pain)
  8. Depressed mood
  9. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  10. Pain

What are the common drug interactions of Prilosec and Amnesteem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Death
  2. Abdominal discomfort
  3. Chapped lips (cracking, fissuring, and peeling of the skin f lip)
  4. Diarrhoea
  5. Mood altered (changes in mood)
  6. Nausea (feeling of having an urge to vomit)
  7. Overdose
  8. Suicide attempt

20-29:

  1. Anxiety
  2. Cholecystitis chronic (long lasting infection of gallbladder)
  3. Emotional distress
  4. Gallbladder injury
  5. General physical health deterioration (weak health status)
  6. Injury
  7. Pain
  8. Pancreatitis (inflammation of pancreas)

30-39:

  1. Suicidal ideation
  2. Depression
  3. Mood altered (changes in mood)
  4. Adverse drug reaction
  5. Arthralgia (joint pain)
  6. Deafness
  7. Fatigue (feeling of tiredness)
  8. Muscular weakness (muscle weakness)
  9. Myalgia (muscle pain)
  10. Tinnitus (a ringing in the ears)

40-49:

  1. Depressed mood
  2. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  3. Pain
  4. Anxiety
  5. Blood triglycerides increased
  6. Arthralgia (joint pain)
  7. Anger
  8. Costochondritis (chest wall pain)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal impairment (severely reduced kidney function)
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  5. Renal disorder (kidney disease)
  6. Arthralgia (joint pain)
  7. Pain in extremity

60+:

n/a

What are the existing conditions these people have? *

  1. Acne Cystic (skin problems that cause pimples): 6 people, 25.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 8.33%
  3. Hypersensitivity: 2 people, 8.33%
  4. High Blood Pressure: 2 people, 8.33%
  5. High Blood Cholesterol: 2 people, 8.33%
  6. Gastric Ph Decreased: 2 people, 8.33%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.33%
  8. Bone Sarcoma (bone cancer): 2 people, 8.33%
  9. Bone Disorder: 2 people, 8.33%
  10. Asthma: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prilosec and Amnesteem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amnesteem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prilosec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amnesteem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on omeprazole and isotretinoin (the active ingredients of Prilosec and Amnesteem, respectively), and Prilosec and Amnesteem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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