Prilosec and Descovy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Descovy (emtricitabine; tenofovir alafenamide fumarate). Common drug interactions include anxiety among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Descovy. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

What is Descovy?

Descovy has active ingredients of emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 14,260 Descovy users. Check the latest studies of Descovy.

On Jul, 26, 2026

46 people who take Prilosec and Descovy together, and have interactions are studied.

What are the common drug interactions of Prilosec and Descovy, by gender? *:

female:

Anxiety
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Chronic kidney disease
Bone density decreased
Depression
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone loss
Depression
Myalgia (muscle pain)
Tooth loss
Hallucination, auditory (perceiving sounds without auditory stimulus)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Pain in extremity
Polyarteritis nodosa (progressive disease of connective tissue)

What are the common drug interactions of Prilosec and Descovy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Anal chlamydia infection (rectal chlamydial infection)
Bone density decreased
Bone loss
Drug ineffective
Genotype drug resistance test positive
Hiv test positive
Proctitis gonococcal (inflammation of the rectum and anus by pus-producing bacterium that causes gonorrhoea)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

40-49:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Chronic kidney disease
Bone density decreased
Bone loss
Foot fracture
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)

50-59:

Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Chronic kidney disease
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Foot fracture
Pain in extremity
Bone density decreased

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Osteoporosis (bones weak and more likely to break)
Rib fracture
Stress
Hip fracture
Insomnia (sleeplessness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Rash erythematous (redness of the skin)
Vitamin d deficiency

What are the existing conditions these people have? *

Indigestion: 7 people, 15.22%
Depression: 7 people, 15.22%
High Blood Pressure: 6 people, 13.04%
High Blood Cholesterol: 6 people, 13.04%
Pain: 5 people, 10.87%
Hepatitis B: 5 people, 10.87%
Neuralgia (pain in one or more nerves): 4 people, 8.70%
Diabetes: 4 people, 8.70%
Asthma: 4 people, 8.70%
Stress And Anxiety: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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