Prilosec and Febuxostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Febuxostat (febuxostat). Common drug interactions include thrombosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Febuxostat. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

On Jul, 26, 2026

51 people who take Prilosec and Febuxostat together, and have interactions are studied.

Prilosec and Febuxostat drug interactions.

What are the common drug interactions of Prilosec and Febuxostat, by gender? *:

female:

Thrombosis (formation of a blood clot inside a blood vessel)
Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Fatigue (feeling of tiredness)
Renal tubular necrosis (death of kidney tubules)
Blood pressure increased
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Nephropathy (damage to or disease of a kidney)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Cardiac failure chronic
Fall
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Loss of consciousness
Skin cancer
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Nephropathy (damage to or disease of a kidney)
Abdominal pain upper

What are the common drug interactions of Prilosec and Febuxostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephropathy (damage to or disease of a kidney)

40-49:

Chronic kidney disease

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Fall
Loss of consciousness
Nephritis (inflammation of the nephrons in the kidneys)
Skin cancer
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal pain upper
Adrenal disorder
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Bursa disorder
Contusion (a type of hematoma of tissue in which capillaries)
Type 2 diabetes mellitus
Anaemia (lack of blood)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Arrhythmia (irregular heartbeat)
Cardiac failure chronic
Cardiac failure congestive

What are the existing conditions these people have? *

Pain: 17 people, 33.33%
High Blood Pressure: 16 people, 31.37%
High Blood Cholesterol: 11 people, 21.57%
Gout (uric acid crystals building up in the body): 10 people, 19.61%
Diabetes: 7 people, 13.73%
Hypersensitivity: 6 people, 11.76%
Immunodeficiency Common Variable: 6 people, 11.76%
Inflammation: 6 people, 11.76%
Fluid Retention (an abnormal accumulation of fluid in the blood): 6 people, 11.76%
Blood Pressure Abnormal: 6 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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