Prilosec and Golytely drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Golytely (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous). Common drug interactions include mental disorder among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Golytely. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,286 Prilosec users. Check the latest studies of Prilosec.

What is Golytely?

Golytely has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride; sodium sulfate, anhydrous. eHealthMe is studying from 907 Golytely users. Check the latest studies of Golytely.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

73 people who take Prilosec and Golytely together, and have interactions are studied.

Prilosec and Golytely drug interactions.

What are the common drug interactions of Prilosec and Golytely, by gender? *:

female:

Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Tendon disorder (disease of tendon)
Essential hypertension (primary hypertension)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Constipation
Dizziness
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Inflammation
Panic reaction

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hepatomegaly (abnormal enlargement of the liver)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Cough
Headache (pain in head)
Hepatic mass
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

What are the common drug interactions of Prilosec and Golytely, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal distension
Alopecia (absence of hair from areas of the body)
Bacterial infection
Blood creatine phosphokinase increased
Dry eye (lack of adequate tears)
Dyspepsia (indigestion)
Gastrointestinal infection (infection of stomach and intestine)
Insomnia (sleeplessness)
Weight decreased

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephropathy (damage to or disease of a kidney)
Anxiety
Palpitations (feelings or sensations that your heart is pounding or racing)
Precancerous skin lesion
Surgery

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Abdominal pain
Constipation
Oedema peripheral (superficial swelling)

50-59:

Epididymitis (pain in the scrotum or testicle)
Epistaxis (bleed from the nose)
Exostosis (formation of new bone on the surface of a bone)
Facet joint syndrome (problem with movement of the facet joints of the spine)
Frequent bowel movements
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Groin pain
Headache (pain in head)
Heart rate irregular
Hyperhidrosis (abnormally increased sweating)

60+:

Chronic kidney disease
Constipation
Hepatic mass
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Renal artery occlusion (obstruction of renal artery)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Back disorder

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 26.03%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 18 people, 24.66%
Pain: 17 people, 23.29%
High Blood Pressure: 12 people, 16.44%
High Blood Cholesterol: 9 people, 12.33%
Constipation: 9 people, 12.33%
Infection: 9 people, 12.33%
Muscle Spasms (muscle contraction): 6 people, 8.22%
Diabetes: 6 people, 8.22%
Hypersensitivity: 5 people, 6.85%

* Approximation only. Some reports may have incomplete information.

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