Prilosec and Perphenazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Perphenazine (perphenazine). Common drug interactions include pleural effusion among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Perphenazine. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,286 Prilosec users. Check the latest studies of Prilosec.

What is Perphenazine?

Perphenazine has active ingredients of perphenazine. It is often used in bipolar i disorder. eHealthMe is studying from 2,712 Perphenazine users. Check the latest studies of Perphenazine.

On Aug, 11, 2026

48 people who take Prilosec and Perphenazine together, and have interactions are studied.

Prilosec and Perphenazine drug interactions.

What are the common drug interactions of Prilosec and Perphenazine, by gender? *:

female:

Pleural effusion (water on the lungs)
Pyrexia (fever)
Abdominal pain
Activities of daily living impaired
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Aggression
Agitation (state of anxiety or nervous excitement)
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia macrocytic (a macrocytic class of anaemia)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Breath odour
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac arrest
Cataract (clouding of the lens inside the eye)
Cerebral atrophy (decrement in size of brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased activity
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the common drug interactions of Prilosec and Perphenazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Chronic kidney disease
Depression
Renal failure (kidney dysfunction)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Alopecia (absence of hair from areas of the body)
Cardiac murmur (an heart sound in valve abnormality)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Multi-organ failure (multisystem organ failure)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hyperglycaemia (high blood sugar)
Hyperlipidaemia (presence of excess lipids in the blood)
Type 2 diabetes mellitus

40-49:

Chronic kidney disease
Death
Renal injury (kidney injury)
Syncope (loss of consciousness with an inability to maintain postural tone)
Renal failure (kidney dysfunction)
Diarrhoea
Lactic acidosis (low ph in body tissues)
Overdose
Weakness

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Disease progression
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)
Eating disorder
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Epidural lipomatosis (excessive accumulation of fat within the epidural space -brain)
Exostosis (formation of new bone on the surface of a bone)
Fungal infection

60+:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Renal failure acute (rapid kidney dysfunction)
Dysarthria (speech disorder)
Facial paresis (weakness in facial muscle movement)
Pyuria (a condition of urine containing pus)
Delirium (wild excitement)
Atelectasis (partial or complete collapse of the lung)
Nausea (feeling of having an urge to vomit)
Pleural effusion (water on the lungs)
Pyrexia (fever)

What are the existing conditions these people have? *

Pain: 14 people, 29.17%
Metastases To Bone (cancer spreads to bone): 9 people, 18.75%
High Blood Pressure: 6 people, 12.50%
High Blood Cholesterol: 4 people, 8.33%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.25%
Depression: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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