Prilosec and Rogaine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Rogaine (minoxidil). Common drug interactions include gingival swelling among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Rogaine. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,286 Prilosec users. Check the latest studies of Prilosec.

What is Rogaine?

Rogaine has active ingredients of minoxidil. It is often used in hair loss. eHealthMe is studying from 34,083 Rogaine users. Check the latest studies of Rogaine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

79 people who take Prilosec and Rogaine together, and have interactions are studied.

What are the common drug interactions of Prilosec and Rogaine, by gender? *:

female:

Gingival swelling (gums swelling)
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Haematoma (collection of blood outside the blood vessels)
Haematuria (presence of blood in urine)
Haemophilus infection (bacterial infection by haemophilus influenzae)
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)

male:

Drug ineffective
Dandruff
Diarrhoea
Dry mouth
Dysarthria (speech disorder)
Dysuria (painful or difficult urination)
Nausea (feeling of having an urge to vomit)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Syncope (loss of consciousness with an inability to maintain postural tone)
Vomiting

What are the common drug interactions of Prilosec and Rogaine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Asthma
Drug dependence

30-39:

Burning sensation
Flushing (the warm, red condition of human skin)

40-49:

Anuria (failure of the kidneys to produce urine)
Blood pressure increased
Dry mouth
Nausea (feeling of having an urge to vomit)
Syncope (loss of consciousness with an inability to maintain postural tone)
Vomiting
Feeling hot
Confusion
Renal disorder (kidney disease)
Renal impairment (severely reduced kidney function)

50-59:

Chest pain
Drug ineffective
Abdominal discomfort
Balance disorder
Diarrhoea
Dysarthria (speech disorder)
Dysuria (painful or difficult urination)
Fatigue (feeling of tiredness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

60+:

Drug ineffective
Pruritus (severe itching of the skin)
Dry skin
Erythema (redness of the skin)
Pain
Scab (a hard coating on the skin formed during the wound healing)
Headache (pain in head)
Hair disorder
Wound
Application site pain

What are the existing conditions these people have? *

High Blood Cholesterol: 15 people, 18.99%
High Blood Pressure: 10 people, 12.66%
Indigestion: 9 people, 11.39%
Thyroid Diseases: 8 people, 10.13%
Multiple Allergies (allergy to multiple agents): 7 people, 8.86%
Pain: 6 people, 7.59%
Depression: 6 people, 7.59%
Cardiac Disorder: 6 people, 7.59%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 6.33%
Diabetes: 5 people, 6.33%

* Approximation only. Some reports may have incomplete information.

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