Prilosec and Sublimaze drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Sublimaze (fentanyl citrate). Common drug interactions include pulmonary arterial hypertension among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Sublimaze. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

What is Sublimaze?

Sublimaze has active ingredients of fentanyl citrate. eHealthMe is studying from 560 Sublimaze users. Check the latest studies of Sublimaze.

On Jul, 29, 2026

59 people who take Prilosec and Sublimaze together, and have interactions are studied.

Prilosec and Sublimaze drug interactions.

What are the common drug interactions of Prilosec and Sublimaze, by gender? *:

female:

Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Syncope (loss of consciousness with an inability to maintain postural tone)
Anaemia (lack of blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Pulmonary embolism (blockage of the main artery of the lung)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Acute hepatic failure
Coma (state of unconsciousness lasting more than six hours)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Bladder cancer
Drug hypersensitivity
Renal disorder (kidney disease)
Bipolar disorder (mood disorder)
Death
Dyspepsia (indigestion)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Renal injury (kidney injury)

What are the common drug interactions of Prilosec and Sublimaze, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Acute hepatic failure
Arthralgia (joint pain)
Aspartate aminotransferase increased
Decreased appetite
Encephalopathy (functioning of the brain is affected by some agent or condition)
Epistaxis (bleed from the nose)
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypercalcaemia (elevated calcium (ca+) level in the blood)

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Anxiety
Depression
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic failure (liver failure)
Renal injury (kidney injury)

40-49:

Abdominal pain
Bladder cancer
Chronic kidney disease
Drug hypersensitivity
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Dyspepsia (indigestion)
Renal injury (kidney injury)
Feeling cold
Neuropathy peripheral (surface nerve damage)
Pain
Pruritus (severe itching of the skin)
Staphylococcal infection (an infection with staphylococcus bacteria)
Bradycardia (abnormally slow heart action)
Presyncope
Agitation (state of anxiety or nervous excitement)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Blood glucose increased
Cardiogenic shock (inadequate circulation of blood)
Carotid artery occlusion (artery blockage)
Carotid artery stenosis (narrowing of carotid artery)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Hypophagia (reduced food intake)
Hypoxia (low oxygen in tissues)
Loss of consciousness

What are the existing conditions these people have? *

Pain: 21 people, 35.59%
High Blood Pressure: 17 people, 28.81%
Nausea (feeling of having an urge to vomit): 8 people, 13.56%
Insomnia (sleeplessness): 7 people, 11.86%
Headache (pain in head): 7 people, 11.86%
High Blood Cholesterol: 7 people, 11.86%
Cardiac Disorder: 5 people, 8.47%
Constipation: 5 people, 8.47%
Gastric Disorder (disease of stomach): 5 people, 8.47%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 8.47%

* Approximation only. Some reports may have incomplete information.

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